Circadian rhythms and sleep are fundamental biological processes integral to human
health. Their disruption is associated with detrimental physiological consequences …

Insomnia disorder affects a large proportion of the population on a situational, recurrent or
chronic basis and is among the most common complaints in medical practice. The disorder …

Chronic insomnia is defined by difficulties in falling asleep, maintaining sleep, and early
morning awakening, and is coupled with daytime consequences such as fatigue, attention …

Insomnia disorder is characterized by chronic dissatisfaction with sleep quantity or quality
that is associated with difficulty falling asleep, frequent nighttime awakenings with difficulty …

Background Sleep restriction is associated with development of metabolic ill-health, and
hormonal mechanisms may underlie these effects. The aim of this study was to determine …

Insomnia is a stress‐related sleep disorder conceptualised within a diathesis‐stress
framework, which it is thought to result from predisposing factors interacting with …

Type 2 diabetes mellitus (T2DM) rates are three times higher in patients with bipolar
disorder (BD), compared to the general population. This is a major contributing factor to the …

Rationale: Obstructive sleep apnea is a common disorder associated with increased risk for
cardiovascular disease, diabetes, and premature mortality. Although there is strong clinical …

Genome-wide association studies (GWAS) in humans have identified loci robustly
associated with several heritable diseases or traits, yet little is known about the functional …

Gliomas, the most common CNS (central nerve system) tumors, face poor survival due to
severe chemoresistance exacerbated by hypoxia. However, studies on whether altered …