[HTML][HTML] Beneath the radar: immune-evasive cell sources for stroke therapy

BA Buil, NH Rentsch, RZ Weber, C Rickenbach… - Trends in Molecular …, 2024 - cell.com
Stem cell therapy is an emerging treatment paradigm for stroke patients with remaining
neurological deficits. While allogeneic cell transplants overcome the manufacturing …

An overview of programmed cell death: apoptosis and pyroptosis—Mechanisms, differences, and significance in organism physiology and pathophysiology

S Kowalski, J Karska, Z Łapińska… - Journal of Cellular …, 2023 - Wiley Online Library
Regulated cell death is an essential and heterogeneous process occurring in the life cycle of
organisms, from embryonic development and aging to the regulation of homeostasis and …

Caspase-9 driven murine model of selective cell apoptosis and efferocytosis

L Batoon, AJ Koh, R Kannan, LK McCauley… - Cell death & …, 2023 - nature.com
Apoptosis and efficient efferocytosis are integral to growth, development, and homeostasis.
The heterogeneity of these mechanisms in different cells across distinct tissues renders it …

Dapagliflozin ameliorates diabetes-induced spermatogenic dysfunction by modulating the adenosine metabolism along the gut microbiota-testis axis

Z Jin, Y Cao, Q Wen, H Zhang, Z Fang, Q Zhao, Y Xi… - Scientific Reports, 2024 - nature.com
Male infertility is one of the most common complications of diabetes mellitus (DM).
Dapagliflozin is widely used to manage the type II DM. This study aimed to assess the …

Caspase-9 suppresses metastatic behavior of MDA-MB-231 cells in an adaptive organoid model

F Falahi, S Akbari-Birgani, Y Mortazavi, B Johari - Scientific Reports, 2024 - nature.com
Abstract Caspase-9, a cysteine-aspartate protease traditionally associated with intrinsic
apoptosis, has recently emerged as having non-apoptotic roles, including influencing cell …

Recovery of structural integrity of epithelial monolayer in response to massive apoptosis-induced defects

Y Yuan, YL Han, J Xia, H Li, C Tang, F Ye, DA Weitz… - BioRxiv, 2022 - biorxiv.org
Apoptosis exists ubiquitously in organisms and plays an essential role in maintaining the
homeostasis of functional tissues. While the signaling pathway of cell apoptosis has been …