A model to estimate the outcome of prostate cancer photodynamic therapy with TOOKAD Soluble WST11

N Betrouni, R Lopes, P Puech, P Colin… - Physics in Medicine & …, 2011 - iopscience.iop.org
Interstitial photodynamic therapy is becoming an interesting modality to treat some early
stage prostate cancers. A light-sensitive drug is injected to the patient and activated by light …

Monte Carlo modeling of in vivo protoporphyrin IX fluorescence and singlet oxygen production during photodynamic therapy for patients presenting with superficial …

RM Valentine, CTA Brown, H Moseley… - Journal of …, 2011 - spiedigitallibrary.org
We present protoporphyrin IX (PpIX) fluorescence measurements acquired from patients
presenting with superficial basal cell carcinoma during photodynamic therapy (PDT) …

Precise spatio-temporal control of rapid optogenetic cell ablation with mem-KillerRed in Zebrafish

C Buckley, MT Carvalho, LK Young, SA Rider… - Scientific Reports, 2017 - nature.com
The ability to kill individual or groups of cells in vivo is important for studying cellular
processes and their physiological function. Cell-specific genetically encoded …

The physics of light and sound in the fight against skin cancer

S Pratavieira, MB Requena, MD Stringasci… - Brazilian Journal of …, 2022 - Springer
Multidisciplinary work is necessary for the development and improvement of techniques for
the diagnosis and treatment of diseases, with physics playing a prominent role. For example …

Single LED-based device to perform widefield fluorescence imaging and photodynamic therapy

C Grecco, HH Buzzá, MD Stringasci… - Biophotonics South …, 2015 - spiedigitallibrary.org
Photodynamic therapy (PDT) is a treatment modality that can be indicated for several cancer
types and pre-cancer lesions. One of the main applications of PDT is the treatment of …

Fluorescence evaluations for porphyrin formation during topical PDT using ALA and methyl-ALA mixtures in pig skin models

AKL Fujita, PGS Rodrigues, MB Requena… - Photodiagnosis and …, 2016 - Elsevier
Abstract Background Photodynamic Therapy (PDT) using Aminolevulinic acid (ALA) and
derivative molecules as topical medication and as a precursor of protoporphyrin (PPIX), is …

Vascular targeted photodynamic therapy with TOOKAD® Soluble (WST11) in localized prostate cancer: efficiency of automatic pre-treatment planning

N Betrouni, S Boukris, F Benzaghou - Lasers in Medical Science, 2017 - Springer
Vascular targeted photodynamic therapy (VTP) with WST11 is a novel non-thermal focal
treatment for localized prostate cancer that has shown favorable and early efficacy results in …

Photobleaching and phototoxicity of KillerRed in tumor spheroids induced by continuous wave and pulsed laser illumination

DS Kuznetsova, MV Shirmanova… - Journal of …, 2015 - Wiley Online Library
The purpose of this study was to evaluate photobleaching of the genetically encoded
photosensitizer KillerRed in tumor spheroids upon pulsed and continuous wave (CW) laser …

Investigating the RAS can be a fishy business: interdisciplinary opportunities using Zebrafish

S Hoffmann, L Mullins, C Buckley, S Rider… - Clinical …, 2018 - portlandpress.com
The renin–angiotensin system (RAS) is highly conserved, and components of the RAS are
present in all vertebrates to some degree. Although the RAS has been studied since the …

[HTML][HTML] Determination of the threshold dose distribution in photodynamic action from in vitro experiments

CMG de Faria, NM Inada, C Kurachi… - Journal of Photochemistry …, 2016 - Elsevier
The concept of threshold in photodynamic action on cells or microorganisms is well
observed in experiments but not fully explored on in vitro experiments. The intercomparison …