This review article focuses on thermoresponsive hydrogels consisting of poloxamers which
are of high interest for biomedical application especially in drug delivery for ophthalmic …

Pluronics are a family of amphiphilic block copolymers broadly explored in the
pharmaceutical field. Under certain conditions, Pluronics self-assemble in different …

Poloxamers are triblock copolymers with a center block of hydrophobic polypropylene oxide
(PPO) flanked by two hydrophilic polyethyleneoxide (PEO) blocks. Among this family of …

A method for the in situ gelation of poloxamers and the mucoadhesive polymer chitosan has
been developed by exploiting the tendency of poloxamer solution to form gel at …

In this study, we reported the development and the physico-chemical characterization of
poloxamer 407 (PL407) and poloxamer 188 (PL188) binary systems as hydrogels for …

The effect of gellan gum on the gelation behavior and in-vitro release of a specific drug
named pilocarpine hydrochloride from different ophthalmic formulations based on …

Glucosamine (GlcN) is a common drug used to treat osteoarthritis (OA). To prolong the
action time of glucosamine on OA and improve its therapeutic effect, this research explored …

The aim of this investigation was to develop a novel in situ gelling formulation based on
poloxamer-407 (PM) for the sustained release of an ophthalmic drug. In an attempt to reduce …

Topical 5% alpha lipoic acid (ALA) has shown efficacy in treatment of photo-damaged skin.
The aim of this work was to evaluate the potential of poloxamer (P407) gel as a vehicle for …

The poly (ethylene oxide)-poly (propylene oxide)-poly (ethylene oxide)(PEO-PPO-PEO)
triblock copolymers, known as poloxamer (Pluronic®), are amphiphilic polymers that …