Preparation and use of decellularized extracellular matrix for tissue engineering

AD McInnes, MAJ Moser, X Chen - Journal of functional biomaterials, 2022 - mdpi.com
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Unlocking exosome-based theragnostic signatures: deciphering secrets of ovarian cancer metastasis

S Mukherjee, S Nag, N Mukerjee, S Maitra… - ACS …, 2023 - ACS Publications
Ovarian cancer (OC) is a common gynecological cancer worldwide. Unfortunately, the lack
of early detection methods translates into a substantial cohort of women grappling with the …

Extracellular vesicles-ceRNAs as ovarian cancer biomarkers: looking into circRNA-miRNA-mRNA code

G Cammarata, N Barraco, I Giusti, V Gristina, V Dolo… - Cancers, 2022 - mdpi.com
Simple Summary Patients with ovarian cancer have a very poor chance of long-term
survival, usually due to advanced disease at the time of diagnosis. Emerging evidence …

Proteomic analysis of ascitic extracellular vesicles describes tumour microenvironment and predicts patient survival in ovarian cancer

A Vyhlídalová Kotrbová, K Gömöryová… - Journal of …, 2024 - Wiley Online Library
High‐grade serous carcinoma of the ovary, fallopian tube and peritoneum (HGSC), the most
common type of ovarian cancer, ranks among the deadliest malignancies. Many HGSC …

Weaving the nest: extracellular matrix roles in pre-metastatic niche formation

L Patras, D Paul, IR Matei - Frontiers in Oncology, 2023 - frontiersin.org
The discovery that primary tumors condition distant organ sites of future metastasis for
seeding by disseminating tumor cells through a process described as the pre-metastatic …

Stem cell-derived extracellular vesicles: a promising nano delivery platform to the brain?

Y Guo, D Hu, L Lian, L Zhao, M Li, H Bao… - Stem cell reviews and …, 2023 - Springer
A very important cause of the frustration with drug therapy for central nervous system (CNS)
diseases is the failure of drug delivery. The blood–brain barrier (BBB) prevents most …

Friend and foe: the regulation network of ascites components in ovarian cancer progression

Z Geng, X Pan, J Xu, X Jia - Journal of Cell Communication and Signaling, 2023 - Springer
The tumor microenvironment (TME) and its complex role in cancer progression have been
hotspots of cancer research in recent years. Ascites, which occurs frequently in patients with …

Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear …

D Zhang, JW Zhang, H Xu, X Chen, Y Gao, HG Jiang… - Molecular Cancer, 2024 - Springer
Background Cellular senescence frequently occurs during anti-cancer treatment, and
persistent senescent tumor cells (STCs) unfavorably promote tumor progression through …

Platelet Activation in Ovarian Cancer Ascites: Assessment of GPIIb/IIIa and PF4 in Small Extracellular Vesicles by Nano-Flow Cytometry Analysis

B Bortot, A Mangogna, B Peacock, R Lees, F Valle… - Cancers, 2022 - mdpi.com
Simple Summary Platelets play a critical role in coagulation and fibrinolysis processes, but
recent literature also indicates their central involvement in immune response, cancer …