MHC and Evolution in Teleosts

U Grimholt - Biology, 2016 - mdpi.com
Major histocompatibility complex (MHC) molecules are key players in initiating immune
responses towards invading pathogens. Both MHC class I and class II genes are present in …

Functional diversity of neuronal cell adhesion and recognition molecule L1CAM through proteolytic cleavage

II Stoyanova, D Lutz - Cells, 2022 - mdpi.com
The neuronal cell adhesion and recognition molecule L1 does not only 'keep cells
together'by way of homophilic and heterophilic interactions, but can also promote cell …

Duloxetine ameliorates valproic acid‐induced hyperactivity, anxiety‐like behavior, and social interaction deficits in zebrafish

TP Joseph, F Zhou, LY Sai, H Chen, SL Lin… - Autism …, 2022 - Wiley Online Library
Syndromic autism spectrum disorders (ASDs) are characterized by impaired social
communication and repetitive/stereotyped behaviors. Currently available therapeutic agents …

[HTML][HTML] Oleanolic acid inhibits mouse spinal cord injury through suppressing inflammation and apoptosis via the blockage of p38 and JNK MAPKs

JL Wang, CH Ren, J Feng, CH Ou, L Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Spinal cord injury (SCI) is reported as a devastating disease, leading to tissue loss and
neurologic dysfunction. However, there is no effective therapeutic strategy for SCI treatment …

Improving tensile properties of a room-temperature formable and heat-treatable Mg–6Zn-0.2 Ca (wt.%) alloy sheet via micro-alloying of Al and Mn

T Nakata, C Xu, S Kamado - Materials Science and Engineering: A, 2020 - Elsevier
We have developed a strong Mg–6Zn-0.2 Ca (wt.%) based alloy sheet with good room-
temperature formability via micro-alloying of Al and Mn. The Al and Mn micro-alloyed Mg …

Regulating axonal responses to injury: the intersection between signaling pathways involved in axon myelination and the inhibition of axon regeneration

SNR Rao, DD Pearse - Frontiers in molecular neuroscience, 2016 - frontiersin.org
Following spinal cord injury (SCI), a multitude of intrinsic and extrinsic factors adversely
affect the gene programs that govern the expression of regeneration-associated genes …

Localising functionalised gold-nanoparticles in murine spinal cords by X-ray fluorescence imaging and background-reduction through spatial filtering for human-sized …

F Grüner, F Blumendorf, O Schmutzler, T Staufer… - Scientific reports, 2018 - nature.com
Accurate in vivo localisation of minimal amounts of functionalised gold-nanoparticles,
enabling eg. early-tumour diagnostics and pharmacokinetic tracking studies, requires a …

Myelin basic protein enhances axonal regeneration from neural progenitor cells

Z Yan, L Chu, X Jia, L Lin, S Cheng - Cell & Bioscience, 2021 - Springer
Introduction Stem cell therapy using neural progenitor cells (NPCs) shows promise in
mitigating the debilitating effects of spinal cord injury (SCI). Notably, myelin stimulates …

Revisiting the proteolytic processing of cell adhesion molecule L1

R Kleene, D Lutz, G Loers, U Bork… - Journal of …, 2021 - Wiley Online Library
The important functions of cell adhesion molecule L1 in the nervous system depend on
diverse proteolytic enzymes which generate different L1 fragments. It has been reported that …

The protective effect of rutin on sciatic nerve injury in acrylamide-exposed rats and its mechanisms

S Dong, C Zhang, Y Wang, S Liu, J Yang, L Li… - Food and Chemical …, 2025 - Elsevier
Rutin (Rut) is a flavonoid with pharmacological activities such as anti-inflammatory and
antioxidant. Acrylamide (ACR) is a toxic substance widely found in human life that can …