Bacterial biofilm inhibition: A focused review on recent therapeutic strategies for combating the biofilm mediated infections

R Srinivasan, S Santhakumari, P Poonguzhali… - Frontiers in …, 2021 - frontiersin.org
Biofilm formation is a major concern in various sectors and cause severe problems to public
health, medicine, and industry. Bacterial biofilm formation is a major persistent threat, as it …

Analysing the eosinophil cationic protein-a clue to the function of the eosinophil granulocyte

J Bystrom, K Amin, D Bishop-Bailey - Respiratory research, 2011 - Springer
Eosinophil granulocytes reside in respiratory mucosa including lungs, in the gastro-intestinal
tract, and in lymphocyte associated organs, the thymus, lymph nodes and the spleen. In …

AMPA: an automated web server for prediction of protein antimicrobial regions

M Torrent, P Di Tommaso, D Pulido, MV Nogués… - …, 2012 - academic.oup.com
AMPA is a web application for assessing the antimicrobial domains of proteins, with a focus
on the design on new antimicrobial drugs. The application provides fast discovery of …

Emerging evidence for pleiotropism of eosinophils

JM Rodrigo-Muñoz, M Gil-Martínez, B Sastre… - International Journal of …, 2021 - mdpi.com
Eosinophils are complex granulocytes with the capacity to react upon diverse stimuli due to
their numerous and variable surface receptors, which allows them to respond in very …

Exploring new biological functions of amyloids: bacteria cell agglutination mediated by host protein aggregation

M Torrent, D Pulido, MV Nogues, E Boix - PLoS pathogens, 2012 - journals.plos.org
Antimicrobial proteins and peptides (AMPs) are important effectors of the innate immune
system that play a vital role in the prevention of infections. Recent advances have …

Eosinophils in infection and intestinal immunity

SP Hogan, A Waddell… - Current opinion in …, 2013 - journals.lww.com
We describe the clinical evidence of eosinophil involvement in IBD, summarize the in-vitro
and in-vivo evidence of eosinophil antibacterial activity and the biology of eosinophils …

Structural dissection of crotalicidin, a rattlesnake venom cathelicidin, retrieves a fragment with antimicrobial and antitumor activity

CB Falcao, C Perez-Peinado… - Journal of medicinal …, 2015 - ACS Publications
In silico dissection of crotalicidin (Ctn), a cathelicidin from a South American pit viper,
yielded fragments Ctn [1–14] and Ctn [15–34], which were tested to ascertain to what extent …

A novel cell-penetrating peptide derived from human eosinophil cationic protein

S Fang, T Fan, HW Fu, CJ Chen, CS Hwang, TJ Hung… - PloS one, 2013 - journals.plos.org
Cell-penetrating peptides (CPPs) are short peptides which can carry various types of
molecules into cells; however, although most CPPs rapidly penetrate cells in vitro, their in …

Rationally modified antimicrobial peptides from the N-terminal domain of human RNase 3 show exceptional serum stability

D Sandín, J Valle, B Chaves-Arquero… - Journal of Medicinal …, 2021 - ACS Publications
Multidrug resistance against conventional antibiotics poses an important threat to human
health. In this context, antimicrobial peptides (AMPs) have been extensively studied for their …

RNase T2 genes from rice and the evolution of secretory ribonucleases in plants

GC MacIntosh, MS Hillwig, A Meyer, L Flagel - Molecular Genetics and …, 2010 - Springer
The plant RNase T2 family is divided into two different subfamilies. S-RNases are involved
in rejection of self-pollen during the establishment of self-incompatibility in three plant …