The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Microelectrode arrays and microprobes have been widely utilized to measure neuronal
activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate …

Human brain organoids replicate much of the cellular diversity and developmental anatomy
of the human brain. However, the physiology of neuronal circuits within organoids remains …

Current electrophysiological or optical techniques cannot reliably perform simultaneous
intracellular recordings from more than a few tens of neurons. Here we report a …

Much development has been directed toward improving the performance and automation of
spike sorting. This continuous development, while essential, has contributed to an over …

Developing a new tool capable of high-precision electrophysiological recording of a large
network of electrogenic cells has long been an outstanding challenge in neurobiology and …

Studies on information processing and learning properties of neuronal networks would
benefit from simultaneous and parallel access to the activity of a large fraction of all neurons …

Mapping brain activity has received growing worldwide interest because it is expected to
improve disease treatment and allow for the development of important neuromorphic …

The analysis of biomedical signals for clinical studies and therapeutic applications can
benefit from embedded devices that can process these signals locally and in real-time. An …

Biological cells are characterized by highly complex phenomena and processes that are, to
a great extent, interdependent. To gain detailed insights, devices designed to study cellular …