Advances in aptamer-mediated targeted delivery system for cancer treatment

S He, Y Du, H Tao, H Duan - International Journal of Biological …, 2023 - Elsevier
Aptamers with high affinity and specificity for certain targets have rapidly become a novel
class of targeted ligands applicated in drug delivery. Based on the excellent characteristics …

Aptamer therapeutics in cancer: current and future

Y Morita, M Leslie, H Kameyama, DE Volk, T Tanaka - Cancers, 2018 - mdpi.com
Aptamer-related technologies represent a revolutionary advancement in the capacity to
rapidly develop new classes of targeting ligands. Structurally distinct RNA and DNA …

Structure-based investigation of a DNA aptamer targeting PTK7 reveals an intricate 3D fold guiding functional optimization

A He, L Wan, Y Zhang, Z Yan, P Guo, D Han… - Proceedings of the …, 2024 - pnas.org
DNA aptamers have emerged as novel molecular tools in disease theranostics owing to
their high binding affinity and specificity for protein targets, which rely on their ability to fold …

Functionalized carbon nanotubes as emerging delivery system for the treatment of cancer

S Mahajan, A Patharkar, K Kuche… - International journal of …, 2018 - Elsevier
In recent time, carbon nanotubes (CNTs) have gained vital importance for pharmaceutical
formulation scientist for delivering drugs and genes, owing to their excellent surface …

Delivery strategies in treatments of leukemia

T Ci, W Zhang, Y Qiao, H Li, J Zang, H Li… - Chemical Society …, 2022 - pubs.rsc.org
Leukemia is a hematological malignancy associated with the uncontrolled proliferation of
mutant progenitors, suppressing the production of normal blood cells. Current treatments …

Nanotechnology-based diagnostics and therapeutics in acute lymphoblastic leukemia: a systematic review of preclinical studies

R Khademi, Z Mohammadi, R Khademi… - Nanoscale …, 2023 - pubs.rsc.org
Background: Leukemia is a malignant disease that threatens human health and life. Nano-
delivery systems improve drug solubility, bioavailability, and blood circulation time, and …

Fabrication of Au/Fe3O4/RGO based aptasensor for measurement of miRNA‐128, a biomarker for acute lymphoblastic leukemia (ALL)

HS Dinani, M Pourmadadi, F Yazdian… - Engineering in Life …, 2022 - Wiley Online Library
Due to their high sensitivity, simplicity, portability, self‐contained, and low cost, the
development of electrochemical biosensors is a beneficial way to diagnose and anticipate …

Aptamer‐targeted DNA nanostructures with doxorubicin to treat protein tyrosine kinase 7‐positive tumours

M Liu, W Ma, Q Li, D Zhao, X Shao, Q Huang… - Cell …, 2019 - Wiley Online Library
Objectives Aptamer sgc8c is a short DNA sequence that can target protein tyrosine kinase 7
(PTK 7), which was overexpressed on many tumour cells. This study aimed to fabricate a …

[HTML][HTML] Applications of electrochemical biosensor of aptamers-based (APTASENSOR) for the detection of leukemia biomarker

Y Nur, S Gaffar, YW Hartati, T Subroto - Sensing and Bio-Sensing Research, 2021 - Elsevier
Leukemia is a deadly cancer disease, and according to World Health Organization (WHO)
data, there were 437,033 cases across the world in 2018. Early detection of this cancer is …

Progress in cancer drug delivery based on AS1411 oriented nanomaterials

X Tong, L Ga, J Ai, Y Wang - Journal of nanobiotechnology, 2022 - Springer
Targeted cancer therapy has become one of the most important medical methods because
of the spreading and metastatic nature of cancer. Based on the introduction of AS1411 and …