[HTML][HTML] Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases

C Wang, M Xu, Q Fan, C Li, X Zhou - Asian journal of pharmaceutical …, 2023 - Elsevier
In the inflammatory microenvironment, there are numerous exosomes secreted by immune
cells (Macrophages, neutrophils, dendritic cells), mesenchymal stem cells (MSCs) and …

Engineering and loading therapeutic extracellular vesicles for clinical translation: A data reporting frame for comparability

M Piffoux, J Volatron, K Cherukula, K Aubertin… - Advanced Drug Delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) have emerged as new drug delivery systems as well as a
regenerative cell-free effectors going beyond academic research to reach industrial …

Neutrophil membrane-derived nanovesicles alleviate inflammation to protect mouse brain injury from ischemic stroke

X Dong, J Gao, CY Zhang, C Hayworth, M Frank… - ACS …, 2019 - ACS Publications
Ischemic stroke is an acute and severe neurological disease, resulting in disability and
death. Reperfusion to an ischemic brain is a means to reverse brain damage after stroke; …

The functional heterogeneity of neutrophil-derived extracellular vesicles reflects the status of the parent cell

F Kolonics, V Szeifert, CI Timár, E Ligeti, ÁM Lőrincz - Cells, 2020 - mdpi.com
Similar to other cell types, neutrophilic granulocytes also release extracellular vesicles
(EVs), mainly medium-sized microvesicles/microparticles. According to published data …

Drug delivery to the inflamed intestinal mucosa–targeting technologies and human cell culture models for better therapies of IBD

O Hartwig, MAS Boushehri, KS Shalaby… - Advanced Drug Delivery …, 2021 - Elsevier
Current treatment strategies for inflammatory bowel disease (IBD) seek to alleviate the
undesirable symptoms of the disorder. Despite the higher specificity of newer generation …

COVID-19 inflammation and implications in drug delivery

M Zoulikha, F Huang, Z Wu, W He - Journal of Controlled Release, 2022 - Elsevier
Growing evidence indicates that hyperinflammatory syndrome and cytokine storm observed
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …

Engineering bacterial membrane nanovesicles for improved therapies in infectious diseases and cancer

J Gao, Y Su, Z Wang - Advanced drug delivery reviews, 2022 - Elsevier
Research on bacterial membrane vesicles (BMVs) is an emerging topic, and the goal is to
address whether BMVs can bring translational tools to improve current therapies. In this …

Human neutrophil membrane-derived nanovesicles as a drug delivery platform for improved therapy of infectious diseases

J Gao, X Dong, Y Su, Z Wang - Acta biomaterialia, 2021 - Elsevier
Resolvins are a group of specialized proresolving lipid mediators (SPMs) enzymatically
produced from omega-3 fatty acids during acute inflammation response to infections or …

Generation, purification and engineering of extracellular vesicles and their biomedical applications

J Gao, X Dong, Z Wang - Methods, 2020 - Elsevier
Extracellular vesicles (EVs), derived from cell membranes, demonstrate the potential to be
excellent therapeutics and drug carriers. Although EVs are promising, the process to …

[HTML][HTML] RGD-expressed bacterial membrane-derived nanovesicles enhance cancer therapy via multiple tumorous targeting

J Gao, S Wang, X Dong, Z Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: A tumor microenvironment is a complicated multicellular system comprised of
tumor cells, immune cells and blood vessels. Blood vessels are the barriers for drug tissue …