A series of novel Ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues (4a-r)
were synthesized by reacting 3, 5-difluoropyridine, with phenacyl bromide to get quaternary …

Abstract A series of 1, 2, 3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were
screened for in vitro whole-cell anti-tubercular activity against the susceptible H37Rv and …

This study investigated the phytochemical content of alcoholic extracts and essential oil of a
new variety of medicinal plants, Agastache foeniculum (Pursh), which Kuntze adapted for …

Candida albicans, an opportunistic fungal pathogen, frequently colonizes immune-
compromised patients and causes mild to severe systemic reactions. Only few antifungal …

A mild, greener approach via tandem-Michael-cyclization cascade reaction towards the
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …

An efficient and facile method is developed to synthesize 3-benzoyl indolizines by two-
component reaction under microwave irradiation. A wide range of substrates could be …

A one-pot three-component method for the synthesis of 3-substituted 2-trifluoromethyl-2, 3-
dihydroimidazo [1, 2-a] pyridin-3-yl analogues from 2-aminopyridine, substituted phenacyl …

According to WHO, in 2021, there was an estimation of 247 million malaria cases from 84
malaria-endemic countries. Globally an estimated count of 2 billion malaria cases and 11.7 …

The cyclooxygenase-2 (COX-2) enzyme is an important target for drug discovery and
development of novel anti-inflammatory agents. Selective COX-2 inhibitors have the …

Tuberculosis (TB) remains the leading cause of death from an infectious disease globally.
The chemotherapy of TB is complicated by the protracted treatment regimens, development …