Hippo signaling was first identified in Drosophila as a key controller of organ size by
regulating cell proliferation and anti-apoptosis. Subsequent studies have shown that this …

Cervical cancer (CC) is a gynecological neoplasm with the highest incidence rate, primarily
attributed to the persistent infection of high-risk Human papillomavirus (HPV). Despite …

The Hippo signaling pathway is a central growth control mechanism in multicellular
organisms. By integrating diverse mechanical, biochemical, and stress cues, the Hippo …

Iron metabolism dysregulation is tightly associated with cancer development. But the
underlying mechanisms remain poorly understood. Increasing evidence has shown that …

Severe viral pneumonia can induce rapid expansion of KRT5+ basal-like cells in small
airways and alveoli; this forms a scar-like structure that persists in the injured alveoli and …

Semaglutide, a glucagon-like peptide-1 receptor agonist, is clinically used as a glucose-
lowering and weight loss medication due to its effects on energy metabolism. In heart failure …

As the downstream effectors of Hippo pathway, YAP/TAZ are identified to participate in
organ growth, regeneration and tumorigenesis. However, owing to lack of a DNA-binding …

SRC is the first identified oncogene, and its aberrant activation has been implicated as a
driving event in tumor initiation and progression. However, its role in cancer stemness …

tert butylphenol (4-tBP), a toxic environmental pollutant estrogen, received widespread
attention due to its widespread presence, environmental persistence, and toxic effect …

Signaling pathways play critical roles in executing and controlling important biological
processes within cells. Cells/organisms trigger appropriate signal transduction pathways in …