Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Benznidazole and nifurtimox are the two approved drugs for their treatment, but both …

To successfully infect, Trypanosoma cruzi evades and modulates the host immune
response. T. cruzi calreticulin (TcCalr) is a multifunctional, endoplasmic reticulum (ER) …

Relatively little is known about the fitness effects and life history trade-offs in medically
important parasites and their insect vectors. One such case is the triatomine bugs and the …

Background: Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is
considered a public health problem in Latin America. In Colombia, it affects more than …

Chagas disease, caused by Trypanosoma cruzi (T. cruzi), affects nearly eight million people
worldwide. There are currently only limited treatment options, which cause several side …

Chagas is an endemic disease in tropical regions of Latin America, caused by the parasite
Trypanosoma cruzi. High intraspecies variability and genome complexity have been …

Trypanosoma cruzi is the causative agent of Chagas disease, a devastating parasitic
disease endemic to Central and South America, Mexico, and the USA. We characterized the …

American trypanosomiasis (AT), also known as Chagas disease, is a vector-borne zoonosis
of global public health importance caused by the protozoan parasite Trypanosoma cruzi (T …

Chagas disease, caused by Trypanosoma cruzi, remains a serious public health problem
worldwide. The parasite was subdivided into six distinct genetic groups, called “discrete …

Chagas disease is caused by Trypanosoma cruzi and affects thousands of people. Drugs
currently used in therapy are toxic and have therapeutic limitations. In addition, the genetic …