Prions, prionoids and protein misfolding disorders

C Scheckel, A Aguzzi - Nature Reviews Genetics, 2018 - nature.com
Prion diseases are progressive, incurable and fatal neurodegenerative conditions. The term
'prion'was first nominated to express the revolutionary concept that a protein could be …

Prions

SB Prusiner - Proceedings of the National Academy of …, 1998 - National Acad Sciences
Prions are unprecedented infectious pathogens that cause a group of invariably fatal
neurodegenerative diseases by an entirely novel mechanism. Prion diseases may present …

Soil, food security and human health: a review

MA Oliver, PJ Gregory - European Journal of Soil Science, 2015 - Wiley Online Library
Direct effects of soil or its constituents on human health are through its ingestion, inhalation
or absorption. The soil contains many infectious organisms that may enter the human body …

“What a waste”—can we improve sustainability of food animal production systems by recycling food waste streams into animal feed in an era of health, climate, and …

GC Shurson - Sustainability, 2020 - mdpi.com
Food waste has been a major barrier to achieving global food security and environmental
sustainability for many decades. Unfortunately, food waste has become an even bigger …

Prion diseases of humans and animals: their causes and molecular basis

J Collinge - Annual review of neuroscience, 2001 - annualreviews.org
▪ Abstract Prion diseases are transmissible neurodegenerative conditions that include
Creutzfeldt-Jakob disease (CJD) in humans and bovine spongiform encephalopathy (BSE) …

A general model of prion strains and their pathogenicity

J Collinge, AR Clarke - Science, 2007 - science.org
Prions are lethal mammalian pathogens composed of aggregated conformational isomers of
a host-encoded glycoprotein and which appear to lack nucleic acids. Their unique biology …

Mammalian prions and their wider relevance in neurodegenerative diseases

J Collinge - Nature, 2016 - nature.com
Prions are notorious protein-only infectious agents that cause invariably fatal brain diseases
following silent incubation periods that can span a lifetime. These diseases can arise …

Prions: protein aggregation and infectious diseases

A Aguzzi, AM Calella - Physiological reviews, 2009 - journals.physiology.org
Transmissible spongiform encephalopathies (TSEs) are inevitably lethal neurodegenerative
diseases that affect humans and a large variety of animals. The infectious agent responsible …

Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft

JG Riess - Chemical reviews, 2001 - ACS Publications
After several decades of intensive efforts, safe injectable preparations capable of effectively
delivering O2 to tissues and removing CO2, ie, so-called blood substitutes, appear to be …

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

ON Gill, Y Spencer, A Richard-Loendt, C Kelly… - Bmj, 2013 - bmj.com
Objectives To carry out a further survey of archived appendix samples to understand better
the differences between existing estimates of the prevalence of subclinical infection with …