Carey, Hannah V., Matthew T. Andrews, and Sandra L. Martin. Mammalian Hibernation:
Cellular and Molecular Responses to Depressed Metabolism and Low Temperature. Physiol …

Metabolic rate depression is an important survival strategy for many animal species and a
common element of hibernation, torpor, aestivation, anaerobiosis, diapause, and …

Protein synthesis (PS) has been considered essential to sustain mammalian life, yet was
found to be virtually arrested for weeks in brain and other organs of the hibernating ground …

Bert B. Boyer and Brian M. Barnes s winter approaches and snow fills the air, mammals that
hibernate avoid the energetic demands of maintaining high body temperatures by seeking …

Mammalian hibernators downregulate processes of energy production and consumption
while maintaining cellular homeostasis. Energetic costs of transcription must be balanced …

Hibernators are unique among mammals in their ability to attain, withstand, and reverse low
body temperatures. Hibernators repeatedly cycle between body temperatures near zero …

Hibernation is characterized by prolonged periods of inactivity with concomitantly low
nutrient intake, conditions that would typically result in muscle atrophy combined with a loss …

All small mammalian hibernators periodically rewarm from torpor to high, euthermic body
temperatures for brief intervals throughout the hibernating season. The functional …

Nonshivering thermogenesis in brown adipose tissue (BAT) provides heat through activation
of a mitochondrial uncoupling protein (UCP1), which causes futile electron transport cycles …

Tissue-resident stem cells may enter a dormant state, also known as quiescence, which
allows them to withstand metabolic stress and unfavorable conditions. Similarly, hibernating …