Adipose knockout of H-ferritin improves energy metabolism in mice

B Lu, S Guo, J Zhao, X Wang, B Zhou - Molecular Metabolism, 2024 - Elsevier
Objective Ferritin, the principal iron storage protein, is essential to iron homeostasis. How
iron homeostasis affects the adipose tissue is not well understood. We investigated the role …

[HTML][HTML] Obacunone protects retinal pigment epithelium cells from ultra-violet radiation-induced oxidative injury

DR Huang, CM Dai, SY Li, XF Li - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Abstract Ultra-violet (UV) radiation (UVR) causes significant oxidative injury to retinal
pigment epithelium (RPE) cells. Obacunone is a highly oxygenated triterpenoid limonoid …

Copper infused fabric attenuates inflammation in macrophages

S Zangiabadi, KP Chamoun, K Nguyen, Y Tang… - Plos one, 2023 - journals.plos.org
While inflammation is an important immune response for protection from infections,
excessive or prolonged inflammation can lead to a variety of debilitating diseases including …

[HTML][HTML] The therapeutic value of XL388 in human glioma cells

S Zhong, J Xue, JJ Cao, B Sun, QF Sun, LG Bian… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
XL388 is a highly efficient and orally-available ATP-competitive PI3K-mTOR dual inhibitor.
Its activity against glioma cells was studied here. In established and primary human glioma …

Mitochondrial dysfunction in metabolic disorders

G Murtaza, M Tariq, R Shawahna - Endocrine Disrupting Chemicals …, 2021 - Springer
Mitochondria are the energy houses of cells. Cell functioning and stability are critical
responsibilities of mitochondria. The other functioning of cells includes ATP production …