Hfq is an RNA-binding protein that is common to diverse bacterial lineages and has key
roles in the control of gene expression. By facilitating the pairing of small RNAs with their …

Hfq is a ubiquitous, Sm‐like RNA binding protein found in most bacteria and some archaea.
Hfq binds small regulatory RNAs (sRNAs), facilitates base pairing between sRNAs and their …

The conserved RNA‐binding protein Hfq, originally discovered in Escherichia coli as a host
factor for Qβ replicase, has emerged as a pleiotropic regulator that modulates the stability or …

▪ Abstract Small noncoding RNAs have been found in all organisms, primarily as regulators
of translation and message stability. The most exhaustive searches have taken place in E …

In bacteria, Hfq is a core RNA chaperone that catalyzes the interaction of mRNAs with
regulatory small RNAs (sRNAs). To determine in vivo RNA sequence requirements for Hfq …

Recent studies on Hfq have provided a deeper understanding of the multiple functions of
this pleiotropic post-transcriptional regulator. Insights into the mechanism of Hfq action have …

Heterochromatin is most often associated with eukaryotic organisms. Yet, bacteria also
contain areas with densely protein-occupied chromatin that appear to silence gene …

RNA molecules face difficulties when folding into their native structures. In the cell, proteins
can assist RNAs in reaching their functionally active states by binding and stabilizing a …

Recent studies have lead to the identification of more than 50 small regulatory RNAs in
Escherichia coli. Only a subset of these RNAs has been characterized. However, it is clear …

Research into post‐transcriptional control of mRNAs by small noncoding RNAs (sRNAs) in
the model bacteria Escherichia coli and Salmonella enterica has mainly focused on sRNAs …