Vimentin diversity in health and disease

F Danielsson, MKK Peterson, H Caldeira Araújo… - Cells, 2018 - mdpi.com
Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …

Vimentin as a multifaceted player and potential therapeutic target in viral infections

I Ramos, K Stamatakis, CL Oeste… - International journal of …, 2020 - mdpi.com
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …

Vimentin at the core of wound healing

LS Coelho-Rato, S Parvanian, MK Modi… - Trends in Cell Biology, 2024 - cell.com
As a member of the large family of intermediate filaments (IFs), vimentin has emerged as a
highly dynamic and versatile cytoskeletal protein involved in many key processes of wound …

Impact of vimentin on regulation of cell signaling and matrix remodeling

Z Ostrowska-Podhorodecka, I Ding… - Frontiers in Cell and …, 2022 - frontiersin.org
Vimentin expression contributes to cellular mechanoprotection and is a widely recognized
marker of fibroblasts and of epithelial-mesenchymal transition. But it is not understood how …

Vimentin as a potential target for diverse nervous system diseases

KZ Chen, SX Liu, YW Li, T He, J Zhao… - Neural regeneration …, 2023 - journals.lww.com
Vimentin is a major type III intermediate filament protein that plays important roles in several
basic cellular functions including cell migration, proliferation, and division. Although vimentin …

Mechanical and non‐mechanical functions of filamentous and non‐filamentous vimentin

AE Patteson, A Vahabikashi, RD Goldman… - …, 2020 - Wiley Online Library
Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …

Vimentin takes a hike–Emerging roles of extracellular vimentin in cancer and wound healing

S Parvanian, LS Coelho-Rato, AE Patteson… - Current Opinion in Cell …, 2023 - Elsevier
Vimentin is a cytoskeletal protein important for many cellular processes, including
proliferation, migration, invasion, stress resistance, signaling, and many more. The vimentin …

Astrocyte-derived small extracellular vesicles regulate dendritic complexity through miR-26a-5p activity

A Luarte, R Henzi, A Fernández, D Gaete, P Cisternas… - Cells, 2020 - mdpi.com
In the last few decades, it has been established that astrocytes play key roles in the
regulation of neuronal morphology. However, the contribution of astrocyte-derived small …

Characterization of vimentin-immunoreactive astrocytes in the human brain

LA O'Leary, MA Davoli, C Belliveau, A Tanti… - Frontiers in …, 2020 - frontiersin.org
Astrocytes are commonly identified by their expression of the intermediate filament protein
glial fibrillary acidic protein (GFAP). GFAP-immunoreactive (GFAP-IR) astrocytes exhibit …

In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype

JL Walker, BM Bleaken, AR Romisher… - Molecular biology of …, 2018 - Am Soc Cell Biol
Following injury, mesenchymal repair cells are activated to function as leader cells that
modulate wound healing. These cells have the potential to differentiate to myofibroblasts …