Endothelial cells (ECs) are a heterogeneous population that fulfills many physiological
processes. ECs also actively participate in both innate and adaptive immune responses …

Inflammatory disorders result from continuous inflammation in injured sites. Many molecules
are involved in this process; the inhibition of which could prevent the inflammation …

Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

Background and Purpose—Human umbilical cord blood cells (HUCBC) are rich in stem and
progenitor cells. In this study we tested whether intravenously infused HUCBC enter brain …

Background: IL-17 is a cytokine that has been reported to be produced by T lymphocytes. In
vitro, IL-17 activates fibro-blasts and macrophages for the secretion of GM-CSF, TNF-α, IL …

The contribution of mast cells in the microenvironment of solid malignancies remains
controversial. Here we functionally assess the impact of tumor-adjacent, submucosal mast …

Endothelial cells, by virtue of their capacity to express adhesion molecules and cytokines,
are intricately involved in inflammatory processes. Endothelial cells have been shown to …

UMBILICAL CORD BLOOD STEM/PROGENITOR CELLS of choice in selected high-risk or
recurrent hematologic malignancies, marrow failure syndromes, severe congenital im- It has …

Ischemic stroke is responsible for many deaths and long-term disability world wide.
Development of effective therapy has been the target of intense research. Accumulating …

▪ Abstract Human vascular endothelial cells (EC) basally display class I and II MHC-peptide
complexes on their surface and come in regular contact with circulating T cells. We propose …