Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …

Psychology and neuroscience are concerned with the study of behavior, of internal cognitive
processes, and their neural foundations. However, most laboratory studies use constrained …

Classical models of perceptual decision-making assume that subjects use a single,
consistent strategy to form decisions, or that decision-making strategies evolve slowly over …

Striatal dopamine drives associative learning by acting as a teaching signal. Much work has
focused on simple learning paradigms, including Pavlovian and instrumental learning …

Trial history biases and lapses are two of the most common suboptimalities observed during
perceptual decision-making. These suboptimalities are routinely assumed to arise from …

Computational analysis of cellular activity has developed largely independently of modern
transcriptomic cell typology, but integrating these approaches may be essential for full …

In reversal learning tasks, the behavior of humans and animals is often assumed to be
uniform within single experimental sessions to facilitate data analysis and model fitting …

A classic view of the striatum holds that activity in direct and indirect pathways oppositely
modulates motor output. Whether this involves direct control of movement, or reflects a …

Understanding decision-making is a core goal in both neuroscience and psychology, and
computational models have often been helpful in the pursuit of this goal. While many models …

Animals adaptively integrate sensation, planning, and action to navigate toward goal
locations in ever-changing environments, but the functional organization of cortex …