Galectins are a family of carbohydrate-binding proteins with an affinity for β-galactosides.
Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and …

Endothelial cells (ECs) are a heterogeneous population that fulfills many physiological
processes. ECs also actively participate in both innate and adaptive immune responses …

The galectins are a family of carbohydrate-binding proteins that are distributed widely in
metazoan organisms. Each galectin exhibits a specific pattern of expression in various cells …

Purpose.: As part of ongoing studies on proteomic alterations during glaucomatous
neurodegeneration, this study focused on the complement system. Methods.: Human retinal …

Over the last decade a vast amount of reports have shown that galectin-1 and galectin-3 are
important mediators of inflammation. In this review we describe how the galectins may be …

In recent years, anew'pathway for complement activation mediated by the mannose-binding
lectin (MBL) has been described as a key mechanism for the mammalian acute phase …

Galectin-8 belongs to the family of tandem-repeat type galectins. It consists as several
isoforms, each made of two domains of∼ 140 amino-acids, both having a carbohydrate …

Galectins constitute a family of evolutionarily conserved animal lectins, which are defined by
their affinity for poly-N-acetyllactosamine-enriched glycoconjugates and sequence …

The members of the galectin family are associated with diverse cellular events, including
immune response. We investigated the effects of galectin-8 on neutrophil function. Human …

Galectins are a family of animal lectins defined by two properties: shared amino acid
sequences in their carbohydrate-recognizing domain, and β-galactoside affinity. A wide …