HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Epicardial adipose tissue: clinical biomarker of cardio-metabolic risk

AC Villasante Fricke, G Iacobellis - International journal of molecular …, 2019 - mdpi.com
Epicardial adipose tissue (EAT) is part of the visceral adipose tissue (VAT) that surrounds
the heart and it is a quantifiable, modifiable, and multifaceted tissue that has both local and …

Visceral adipose tissue as a source of inflammation and promoter of atherosclerosis

N Alexopoulos, D Katritsis, P Raggi - Atherosclerosis, 2014 - Elsevier
The current epidemic of obesity with the associated increasing incidence of insulin
resistance, diabetes mellitus and atherosclerosis affecting a large proportion of the North …

Obesity and weight gain in persons with HIV

SS Bailin, CL Gabriel, CN Wanjalla… - Current HIV/AIDS Reports, 2020 - Springer
Abstract Purpose of Review The proportion of overweight and obese persons with HIV
(PWH) has increased since the introduction of antiretroviral therapy (ART). We aim to …

Epicardial fat: definition, measurements and systematic review of main outcomes

AG Bertaso, D Bertol, BB Duncan… - Arquivos brasileiros de …, 2013 - SciELO Brasil
Epicardial fat (EF) is a visceral fat deposit, located between the heart and the pericardium,
which shares many of the pathophysiological properties of other visceral fat deposits, It also …

Cardiovascular disease in HIV patients: from bench to bedside and backwards

E Cerrato, A Calcagno, F D'ascenzo… - Open …, 2015 - openheart.bmj.com
HIV patients are exposed to a higher risk of adverse cardiovascular events, due to complex
interactions between traditional risk factors and HIV infection itself in terms of ongoing …

Pathophysiology and management of cardiovascular disease in patients with HIV

E Nou, J Lo, C Hadigan, SK Grinspoon - The lancet Diabetes & …, 2016 - thelancet.com
Results from several studies have suggested that people with HIV have an increased risk of
cardiovascular disease, especially coronary heart disease, compared with people not …

Diabetes in HIV: the link to weight gain

SS Bailin, JR Koethe - Current HIV/AIDS Reports, 2023 - Springer
Abstract Purpose of Review The burden of metabolic diseases, including type 2 diabetes
mellitus (T2DM), is rising among persons with HIV (PWH) on antiretroviral therapy (ART) …

[PDF][PDF] Morbidity in older HIV-infected patients: impact of long-term antiretroviral use

G Guaraldi, M Prakash, C Moecklinghoff, HJ Stellbrink - Aids Rev, 2014 - researchgate.net
The introduction of HAART has represented a major advance in the care of people with HIV.
By markedly increasing life expectancy, HAART has significantly changed the pattern of HIV …

Exercise to prevent accelerated vascular aging in people living with HIV

R Jones, AT Robinson, LB Beach, ML Lindsey… - Circulation …, 2024 - Am Heart Assoc
Given advances in antiretroviral therapy, the mortality rate for HIV infection has dropped
considerably over recent decades. However, people living with HIV (PLWH) experience …