The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?

NC Peeri, N Shrestha, MS Rahman… - International journal …, 2020 - academic.oup.com
Objectives To provide an overview of the three major deadly coronaviruses and identify
areas for improvement of future preparedness plans, as well as provide a critical …

Natural antioxidant evaluation: A review of detection methods

JS Mendonça, RCA Guimarães, VA Zorgetto-Pinheiro… - Molecules, 2022 - mdpi.com
Antioxidants have drawn the attention of the scientific community due to being related to the
prevention of various degenerative diseases. The antioxidant capacity has been extensively …

Lipid peroxidation: its mechanism, measurement, and significance

B Halliwell, S Chirico - The American journal of clinical nutrition, 1993 - Elsevier
An increased concentration of end products of lipid peroxidation is the evidence most
frequently quoted for the involvement of free radicals in human disease. However, it is likely …

The biochemistry and medical significance of the flavonoids

BH Havsteen - Pharmacology & therapeutics, 2002 - Elsevier
Flavonoids are plant pigments that are synthesised from phenylalanine, generally display
marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are …

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

DM Hockenbery, ZN Oltvai, XM Yin, CL Milliman… - Cell, 1993 - cell.com
Bcl-2 inhibits most types of apoptotic cell death, implying a common mechanism of lethality.
Bcl-2 is localized to intracellular sites of oxygen free radical generation including …

Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

M Tiedge, S Lortz, J Drinkgern, S Lenzen - Diabetes, 1997 - Am Diabetes Assoc
Antioxidant enzyme expression was determined in rat pancreatic islets and RINm5F insulin-
producing cells on the level of mRNA, protein, and enzyme activity in comparison with 11 …

Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress

C Michiels, M Raes, O Toussaint, J Remacle - Free radical Biology and …, 1994 - Elsevier
Eukaryotic cells have to constantly cope with highly reactive oxygen-derived free radicals.
Their defense against these free radicals is achieved by natural antioxidant molecules but …

[HTML][HTML] Oxidative stress in the pathogenesis of skin disease

DR Bickers, M Athar - Journal of investigative dermatology, 2006 - Elsevier
Skin is the largest body organ that serves as an important environmental interface providing
a protective envelope that is crucial for homeostasis. On the other hand, the skin is a major …

Oxidative stress and gene regulation

RG Allen, M Tresini - Free Radical Biology and Medicine, 2000 - Elsevier
Reactive oxygen species are produced by all aerobic cells and are widely believed to play a
pivotal role in aging as well as a number of degenerative diseases. The consequences of …

Biologically relevant metal ion-dependent hydroxyl radical generation An update

B Halliwell, JMC Gutteridge - FEBS letters, 1992 - Elsevier
Transition metal ions, especially iron, appear to be important mediators of oxidative damage
in vivo. Iron (II) reacts with H 2 O 2 to give more-reactive radicals. On the basis of ESR spin …