Hepatic fibrosis 2022: Unmet needs and a blueprint for the future

SL Friedman, M Pinzani - Hepatology, 2022 - Wiley Online Library
Steady progress over four decades toward understanding the pathogenesis and clinical
consequences of hepatic fibrosis has led to the expectation of effective antifibrotic drugs, yet …

A researcher's guide to preclinical mouse NASH models

S Gallage, JEB Avila, P Ramadori, E Focaccia… - Nature …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) and its inflammatory form, non-alcoholic
steatohepatitis (NASH), have quickly risen to become the most prevalent chronic liver …

[HTML][HTML] Artificial intelligence in gastroenterology: A state-of-the-art review

PT Kröner, MML Engels, BS Glicksberg… - World journal of …, 2021 - ncbi.nlm.nih.gov
The development of artificial intelligence (AI) has increased dramatically in the last 20 years,
with clinical applications progressively being explored for most of the medical specialties …

[HTML][HTML] Emerging early diagnostic methods for acute kidney injury

Z Xiao, Q Huang, Y Yang, M Liu, Q Chen, J Huang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Many factors such as trauma and COVID-19 cause acute kidney injury (AKI). Late AKI have
a very high incidence and mortality rate. Early diagnosis of AKI provides a critical therapeutic …

Artificial intelligence in gastroenterology and hepatology: how to advance clinical practice while ensuring health equity

E Uche-Anya, A Anyane-Yeboa, TM Berzin… - Gut, 2022 - gut.bmj.com
Artificial intelligence (AI) and machine learning (ML) systems are increasingly used in
medicine to improve clinical decision-making and healthcare delivery. In gastroenterology …

[HTML][HTML] Perspectives on precision medicine approaches to NAFLD diagnosis and management

A Lonardo, JP Arab, M Arrese - Advances in Therapy, 2021 - Springer
Precision medicine defines the attempt to identify the most effective approaches for specific
subsets of patients based on their genetic background, clinical features, and environmental …

NASH drug treatment development: challenges and lessons

H Tilg, CD Byrne, G Targher - The Lancet Gastroenterology & …, 2023 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver
disease worldwide. Although NAFLD is tightly linked to obesity and type 2 diabetes, this liver …

Tracing the evolution of ai and machine learning applications in advancing materials discovery and production processes

N Ninduwezuor-Ehiobu, OA Tula… - Engineering Science & …, 2023 - fepbl.com
This research paper examines the transformative role of artificial intelligence (AI) and
machine learning (ML) in advancing materials discovery and production processes. The …

Artificial intelligence in precision medicine in hepatology

TH Su, CH Wu, JH Kao - Journal of Gastroenterology and …, 2021 - Wiley Online Library
The advancement of investigation tools and electronic health records (EHR) enables a
paradigm shift from guideline‐specific therapy toward patient‐specific precision medicine …

An emperor penguin optimizer application for medical diagnostics

L Jovanovic, M Zivkovic, M Antonijevic… - 2022 IEEE Zooming …, 2022 - ieeexplore.ieee.org
Extreme gradient boosting (XGBoost) is a broadly adopted machine learning approach often
applied to classification problems. It outperforms many contemporary methods with high …