Quinoline anticancer agents active on DNA and DNA-interacting proteins: From classical to emerging therapeutic targets

A Lauria, G La Monica, A Bono, A Martorana - European Journal of …, 2021 - Elsevier
Quinoline is one of the most important and versatile nitrogen heterocycles embodied in
several biologically active molecules. Within the numerous quinolines developed as …

Geometrical structures, thermal properties and spectroscopic studies of Schiff base complexes: Correlation between ionic radius of metal complexes and DNA binding

SM Morgan, AZ El-Sonbati, HR Eissa - Journal of Molecular Liquids, 2017 - Elsevier
A novel series of transition metal complexes of Cu (II), Co (II), Ni (II), Mn (II) and Cd (II) were
prepared from Schiff base derived from 4-aminoantipyrine and quinoline-2-carbaldehyde to …

High anticancer potency on tumor cells of dehydroabietylamine Schiff-base derivatives and a copper (II) complex

F Zhao, W Wang, W Lu, L Xu, S Yang, XM Cai… - European journal of …, 2018 - Elsevier
Five bioactive dehydroabietylamine Schiff-base derivatives (L 1-L 5) had been synthesized
from Dehydroabietylamine (L 0), and the complex Cu (L 1) 2 had been obtained from the …

Polymer complexes. LXXV. Characterization of quinoline polymer complexes as potential bio-active and anti-corrosion agents

MI Abou-Dobara, NF Omar, MA Diab… - Materials Science and …, 2019 - Elsevier
Abstract The Cu 2+, Co 2+, Ni 2+ and UO 2 2+ polymer complexes of 5-(2, 3-dimethyl− 1-
phenylpyrazol-5-one azo)-8-hydroxyquinoline (HL) ligand were prepared and characterized …

Synthesis, DNA binding, and antiproliferative activity of novel acridine-thiosemicarbazone derivatives

SMV Almeida, EA Lafayette… - International journal of …, 2015 - mdpi.com
In this work, the acridine nucleus was used as a lead-compound for structural modification
by adding different substituted thiosemicarbazide moieties. Eight new (Z)-2-(acridin-9 …

Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase …

AG Ribeiro, SMV de Almeida, JF de Oliveira… - European Journal of …, 2019 - Elsevier
Abstract Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were
synthetized and their biological properties were investigated, among which, the ability to …

Synthesis, spectroscopic, thermal properties, Calf thymus DNA binding and quantum chemical studies of M (II) complexes

SM Morgan, MA Diab… - Applied Organometallic …, 2018 - Wiley Online Library
A new series of transition metal complexes of Cu (II), Co (II), Ni (II), Mn (II) and Cd (II) were
prepared from the ligand of 5‐(4‐benzenesulfonic acid azo)‐2‐thioxo‐4‐thiazolidinone …

ROS-mediated cytotoxic effect of copper (II) hydrazone complexes against human glioma cells

AAR Despaigne, JG Da Silva, PR Da Costa… - Molecules, 2014 - mdpi.com
2-Acetylpyridine acetylhydrazone (H2AcMe), 2-benzoylpyridine acetylhydrazone (H2BzMe)
and complexes [Cu (H2AcMe) Cl2](1) and [Cu (H2BzMe) Cl2](2) were assayed for their …

Synthesis, structure and in vitro pharmacological evaluation of a novel 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (2′-methylbenzoyl) hydrazone bridged copper (II) …

DS Raja, E Ramachandran, NSP Bhuvanesh… - European Journal of …, 2013 - Elsevier
A novel ligand bridged copper (II) coordination polymer,[Cu (HL)(NO3)] n has been
synthesized by reacting 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (2′-methylbenzoyl) …

Molecular docking, DNA binding, thermal studies and antimicrobial activities of Schiff base complexes

AZ El-Sonbati, MA Diab, AA El-Bindary… - Journal of Molecular …, 2016 - Elsevier
Abstract Metal (II) complexes of 3-[(2-hydroxy-3-methoxybenzylidene) hydrazo]-1, 3-
dihydroindol-2-one (HL) were prepared, their compositions and physicochemical properties …