Bacterial multidrug efflux pumps at the frontline of antimicrobial resistance: an overview

L Huang, C Wu, H Gao, C Xu, M Dai, L Huang, H Hao… - Antibiotics, 2022 - mdpi.com
Multidrug efflux pumps function at the frontline to protect bacteria against antimicrobials by
decreasing the intracellular concentration of drugs. This protective barrier consists of a …

Physiological functions of bacterial “multidrug” efflux pumps

PJF Henderson, C Maher, LDH Elbourne… - Chemical …, 2021 - ACS Publications
Bacterial multidrug efflux pumps have come to prominence in human and veterinary
pathogenesis because they help bacteria protect themselves against the antimicrobials …

Identification, Typing and Drug Resistance of Cronobacter spp. in Powdered Infant Formula and Processing Environment

H Li, S Fu, D Song, X Qin, W Zhang, C Man, X Yang… - Foods, 2023 - mdpi.com
Cronobacter spp. is a food-borne pathogenic microorganism that can cause serious
diseases such as meningitis, sepsis, and necrotizing colitis in infants and young children …

A major facilitator superfamily (MFS) efflux pump, SCO4121, from Streptomyces coelicolor with roles in multidrug resistance and oxidative stress tolerance and its …

A Nag, S Mehra - Applied and Environmental Microbiology, 2021 - Am Soc Microbiol
Overexpression of efflux pumps is one of the major determinants of resistance in bacteria.
Streptomyces species harbor a large array of efflux pumps that are transcriptionally silenced …

Response of Lactobacillus plantarum WCFS1 to the Gram-Negative Pathogen-Associated Quorum Sensing Molecule N-3-Oxododecanoyl Homoserine Lactone

JR Spangler, SN Dean, DH Leary… - Frontiers in …, 2019 - frontiersin.org
The bacterial quorum sensing phenomenon has been well studied since its discovery and
has traditionally been considered to include signaling pathways recognized exclusively …

Efflux identification and engineering for ansamitocin P-3 production in Actinosynnema pretiosum

X Wang, J Wei, Y Xiao, S Luan, X Ning… - Applied Microbiology and …, 2021 - Springer
Abstract Ansamitocin P-3 (AP-3) exhibits potent biological activities against various tumor
cells. As an important drug precursor, reliable supply of AP-3 is limited by low fermentation …

Involvement of the SCO3366 efflux pump from S. coelicolor in rifampicin resistance and its regulation by a TetR regulator

A Nag, S Mehra - Applied Microbiology and Biotechnology, 2022 - Springer
Overexpression of efflux pumps represents a key mechanism of resistance in bacteria. Soil
bacteria such as Streptomyces harbour a vast array of efflux genes that are transcriptionally …

Characterization and transcriptomic analysis of Streptococcus thermophilus strain EU01 promoted by Eucommia ulmoides Oliv. extract.

ZY Nie, YH Li, L Li, X Zhao - Science Asia, 2021 - search.ebscohost.com
Eucommia ulmoides Oliv. has been extensively studied for its promoting effect on bacterial
growth. A bacterial strain, called EU01, was isolated from the aqueous extract of E. ulmoides …