Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease

LA Videla, R Rodrigo, J Araya, J Poniachik - Free Radical Biology and …, 2004 - Elsevier
Human nonalcoholic fatty liver disease (NAFLD) associated with obesity is characterized by
depletion of hepatic n-3 long-chain polyunsaturated fatty acids (LCPUFA), with lower …

Increase in long-chain polyunsaturated fatty acid n− 6/n− 3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease

J Araya, R Rodrigo, LA Videla, L Thielemann… - Clinical …, 2004 - portlandpress.com
Hepatic steatosis is a major feature associated with NAFLD (non-alcoholic fatty liver
disease). The aims of the present study were to assess the levels of PUFA (polyunsaturated …

Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): a cross-sectional study

JP Allard, E Aghdassi, S Mohammed, M Raman… - Journal of …, 2008 - Elsevier
BACKGROUND/AIMS: Low hepatic n− 6 and n− 3 polyunsaturated fatty acid (PUFA) may
contribute to steatosis and steatohepatitis and can be affected by diet and oxidative stress …

[HTML][HTML] Infant plasma trans, n− 6, and n− 3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and …

SL Elias, SM Innis - The American journal of clinical nutrition, 2001 - Elsevier
Background: Arachidonic acid (AA) and docosahexaenoic acid (DHA) are important for
growth and neural development. trans Fatty acids (TFAs) may inhibit desaturation of linoleic …

Systematic review and meta-analysis of controlled intervention studies on the effectiveness of long-chain omega-3 fatty acids in patients with nonalcoholic fatty liver …

K Musa-Veloso, C Venditti, HY Lee, M Darch… - Nutrition …, 2018 - academic.oup.com
Context Treatment options for nonalcoholic fatty liver disease (NAFLD) are needed.
Objective The aim of this review was to systematically assess the effects of omega-3 long …

Dietary trans fatty acids in early life: a review

E Larque, S Zamora, A Gil - Early human development, 2001 - Elsevier
Trans fatty acids are unsaturated fatty acids with at least a double trans configuration,
resulting in a more rigid molecule close to a saturated fatty acid. These appear in dairy fat …

Trans fatty acids: properties, benefits and risks

M Semma - Journal of health science, 2002 - jstage.jst.go.jp
Trans fatty acids have several beneficial aspects for processed foods owing to their
characteristic structures. These very characteristic structures, in turn, have been suspected …

Regioselective cis− trans isomerization of arachidonic double bonds by thiyl radicals: the influence of phospholipid supramolecular organization

C Ferreri, A Samadi, F Sassatelli, L Landi… - Journal of the …, 2004 - ACS Publications
Trans unsaturated fatty acids in humans may be originated by two different contributions.
The exogenous track is due to dietary supplementation of trans fats and the endogenous …

[HTML][HTML] Trans fatty acids in human milk in Canada declined with the introduction of trans fat food labeling

R Friesen, SM Innis - The Journal of nutrition, 2006 - Elsevier
Trans fatty acids in human milk have raised concerns because of possible adverse effects
on infant growth and development. Analyses of human milk in the late 1990s in Canada …

A comprehensive toxicological analysis of trans-fatty acids (TFAs) reveals a pro-apoptotic action specific to industrial TFAs counteracted by polyunsaturated FAs

Y Hirata, N Kashiwabara, Y Nada, A Inoue, E Sato… - Scientific Reports, 2023 - nature.com
Abstract trans-Fatty acids (TFAs) are unsaturated fatty acids containing at least one carbon–
carbon double bond in trans configuration, which are classified into two groups according to …