Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

MH Mirjalili, E Moyano, M Bonfill, RM Cusido… - Molecules, 2009 - mdpi.com
Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that
has been used in Ayurvedic and indigenous medicine for over 3,000 years. In view of its …

An overview of biotechnological interventions and abiotic elicitors on biomass and withanolide biosynthesis in Withania somnifera (L.) Dunal

L Sharma, B Maurya, SP Rai - Industrial Crops and Products, 2023 - Elsevier
Withania somnifera is a solanaceous plant species having immense therapeutic potential
and commercial values, attributed by pharmacologically active secondary metabolites viz …

Establishment of Withania somnifera Hairy Root Cultures for the Production of Withanolide A

HN Murthy, C Dijkstra, P Anthony… - Journal of integrative …, 2008 - Wiley Online Library
Withania sominifera (Indian ginseng) was transformed by Agrobacterium rhizogenes.
Explants from seedling roots, stems, hypocotyls, cotyledonary nodal segments, cotyledons …

Establishment of cell suspension cultures of Withania somnifera for the production of withanolide A

P Nagella, HN Murthy - Bioresource Technology, 2010 - Elsevier
Cell suspension cultures of Withania somnifera were established in shake flasks and the
effect of different growth regulators (auxins, combination of auxin and cytokinin), inoculum …

[PDF][PDF] Phytochemistry, pharmacology, and biotechnology of Withania somnifera and Withania coagulans: A review

R Jain, S Kachhwaha… - Journal of Medicinal Plants …, 2012 - academicjournals.org
The genus Withania (Family: Solanaceae) is a highly acclaimed genus of medicinal plants in
the Indian Ayurvedic system of medicine because of its valuable pharmaceutical and …

A Decade of Molecular Understanding of Withanolide Biosynthesis and In vitro Studies in Withania somnifera (L.) Dunal: Prospects and Perspectives for Pathway …

N Dhar, S Razdan, S Rana, WW Bhat… - Frontiers in plant …, 2015 - frontiersin.org
Withania somnifera, a multipurpose medicinal plant is a rich reservoir of pharmaceutically
active triterpenoids that are steroidal lactones known as withanolides. Though the plant has …

Withanolide A Biogeneration in in Vitro Shoot Cultures of Ashwagandha (Withania somnifera DUNAL), a Main Medicinal Plant in Ayurveda

RS Sangwan, ND Chaurasiya, P Lal… - Chemical and …, 2007 - jstage.jst.go.jp
Multiple shoot cultures of two experimental lines of Withania somnifera plants (RS-Selection-
1 and RS-Selection-2) were established using nodal segments as explants. The hormonal …

Production of withaferin A in shoot cultures of Withania somnifera

S Ray, S Jha - Planta medica, 2001 - thieme-connect.com
Multiple shoot cultures of Withania somnifera were established from single shoot tip explants
and their potential for the production of two principle withanolides, withaferin A and …

Changes in morphological phenotypes and withanolide composition of Ri-transformed roots of Withania somnifera

M Bandyopadhyay, S Jha, D Tepfer - Plant Cell Reports, 2007 - Springer
Developmental variability was introduced into Withania somnifera using genetic
transformation by Agrobacterium rhizogenes, with the aim of changing withasteroid …

Withanolide A is inherently de novo biosynthesized in roots of the medicinal plant Ashwagandha (Withania somnifera)

RS Sangwan, ND Chaurasiya, P Lal… - Physiologia …, 2008 - Wiley Online Library
Ashwagandha (Withania somnifera Dunal., Solanaceae) is one of the most reputed
medicinal plants of Ayurveda, the traditional medical system. Several of its traditionally …