Reactive oxygen species (ROS) are implicated in inflammatory, autoimmune, and
neurodegenerative diseases. The activation, proliferation, and apoptosis of immune cells …

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease
characterized by autoantibodies directed against various biomolecules. The initial …

Nitration of free and protein associated tyrosine represents, in vivo, a mechanism that can
severely compromise the cell function. The detection of 3‐nitrotyrosine (3‐NT) in …

Peroxynitrite is a potent oxidant and nitrating agent and has in vivo existence. It is a powerful
proinflammatory substance and may increase vascular permeability in inflamed tissues …

Activation, proliferation and programmed cell death of immune cells are dependent on
controlled production of ROS (reactive oxygen species). However, under chronic …