Single agent checkpoint inhibitor therapy has not been effective for most gastrointestinal
solid tumors, but combination therapy with drugs targeting additional immunosuppressive …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

Parkinson's disease (PD) is a common neurodegenerative disease characterized
pathologically by dopaminergic neuron loss and the formation of Lewy bodies, which are …

Alcohol is one of the most commonly abused substances in the United States. Chronic
consumption of ethanol has been responsible for numerous chronic diseases and …

Background Cardiovascular disease constitutes a major cause of death worldwide.
Inflammation plays an important role in atherosclerosis formation, coronary artery disease …

Endometriosis is ectopic growth of endometrial tissue traditionally thought to arise through
retrograde menstruation. We aimed to determine if cells derived from endometriosis could …

The extended infection with Helicobacter pylori (H. pylori), one of the most frequent
infectious agents in humans, may cause gastritis, peptic ulcers, gastric mucosa-associated …

Objective: The role of CXCL12 and its receptor CXCR4 has not been fully examined in
Parkinson's disease (PD). The purpose of this study was to investigate the role of …

The survival and development of a semi‐allogeneic fetus during pregnancy require the
involvement of a series of cytokines and immune cells. Chemokines are a type of special …

Background Colorectal cancer (CRC) is a globally prevalent malignancy, primarily affecting
the colon and rectum, characterized by uncontrolled cellular changes in the intestinal wall …