Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …

We discuss the evolution of OrbitrapTM mass spectrometry (MS) from its birth in the late
1990s to its current role as one of the most prominent techniques for MS. The Orbitrap mass …

Data analysis is a very challenging task in LC-MS metabolomic studies. The use of powerful
analytical techniques (eg, high-resolution mass spectrometry) provides high-dimensional …

Metabolomics aims at detection and quantitation of all metabolites in biological samples.
The presence of metabolites with a wide variety of physicochemical properties and different …

The choice of sample-preparation method is extremely important in metabolomic studies
because it affects both the observed metabolite content and biological interpretation of the …

We present a liquid chromatography− mass spectrometry (LC− MS) method that capitalizes
on the mass-resolving power of the orbitrap to enable sensitive and specific measurement of …

Lipidomics aims to quantitatively define lipid classes, including their molecular species, in
biological systems. Lipidomics has experienced rapid progress, mainly because of …

Recent expansion in research in the field of lipidomics has been driven by the development
of new mass spectrometric tools and protocols for the identification and quantification of …

Metabolomics, along with other “omics” approaches, is rapidly becoming one of the major
approaches aimed at understanding the organization and dynamics of metabolic networks …

Over the past decade the application of non‐targeted high‐throughput metabolomic analysis
within the plant sciences has gained ever increasing interest and has truly established itself …