Abstract Camptothecin (CPT), a well-known monoterpenoid indole alkaloid with broad-
spectrum anti-cancer activity, is produced from plants and endophytes. In view of the …

Natural products continue to be the inspirations for us to discover and acquire new drugs.
The seemingly unstoppable viruses have kept records high to threaten human health and …

The present study explores the influence of mycophenolic acid (MPA) in combination
therapy with quercetin (QC)(impeding MPA metabolic rate) delivered using the liposomal …

Mycophenolic acid (MPA) has promising anticancer properties; however, it has limited
clinical applications in vivo due to hydrophobic nature, high first-pass metabolism, lack of …

Filamentous fungi have been growingly used to produce many compounds we use on a
daily basis, such as antibiotics and enzymes, or even to treat industrial effluents. While some …

Based on the broad clinical utility of the immunosuppressant mycophenolic acid (MPA), this
article aims to intensify the biosynthetic potential of Penicillium roqueforti for more effective …

Different agro-industrial materials were screened for their performance on production of
mycophenolic acid (MPA) by two strains of Penicillium roqueforti (AG101 and LG109) under …

Although Penicillium brevicompactum is a very important industrial strain for mycophenolic
acid production, there are no reports on Ca2+/reactive oxygen species (ROS) synergistic …

Mycophenolic acid (MPA) is an occurring antibiotic produced through Penicillium
brevicompactum. Its production was achieved by systematic process optimization under …

Soil-occupant fungi produce a variety of mycotoxins as secondary metabolites, one of which
is mycophenolic acid (MPA), an antibiotic and immunosuppressive agent. MPA is mainly …