Human organoids: tools for understanding biology and treating diseases

F Schutgens, H Clevers - Annual Review of Pathology …, 2020 - annualreviews.org
Organoids are in vitro–cultured three-dimensional structures that recapitulate key aspects of
in vivo organs. They can be established from pluripotent stem cells and from adult stem …

Liver fluke induces cholangiocarcinoma

B Sripa, S Kaewkes, P Sithithaworn, E Mairiang… - PLoS …, 2007 - journals.plos.org
Liver Fluke Induces Cholangiocarcinoma | PLOS Medicine Skip to main content
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Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection

P Qi, S Cheng, H Wang, N Li, Y Chen, C Gao - PloS one, 2011 - journals.plos.org
Background MicroRNAs (miRNAs) have been shown to anticipate great cancer diagnostic
potential. Recently, circulating miRNAs have been reported as promising biomarkers for …

[HTML][HTML] Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: Subset analyses of the phase III Sorafenib …

AL Cheng, Z Guan, Z Chen, CJ Tsao, S Qin… - European Journal of …, 2012 - Elsevier
BACKGROUND: The phase III Sorafenib Asia–Pacific (AP) trial—conducted in China,
Taiwan and South Korea–confirmed that sorafenib improves overall survival (OS) and is …

National and subnational population-based incidence of cancer in Thailand: assessing cancers with the highest burdens

S Virani, S Bilheem, W Chansaard, I Chitapanarux… - Cancers, 2017 - mdpi.com
In Thailand, five cancer types—breast, cervical, colorectal, liver and lung cancer—contribute
to over half of the cancer burden. The magnitude of these cancers must be quantified over …

Activation of the hedgehog pathway in human hepatocellular carcinomas

S Huang, J He, X Zhang, Y Bian, L Yang, G Xie… - …, 2006 - academic.oup.com
Liver cancers, the majority of which are hepatocellular carcinomas (HCCs), rank as the
fourth in cancer mortality worldwide and are the most rapidly increasing type of cancer in the …

Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma

B Sun, S Zhang, D Zhang, J Du, H Guo… - Oncology …, 2006 - spandidos-publications.com
Vasculogenic mimicry (VM) has increasingly been recognized as a form of angiogenesis. In
VM, epithelial cells are integrated into the malignant tumor vasculature. An association has …

Amitriptyline or Not, That Is the Question: Pharmacogenetic Testing of CYP2D6 and CYP2C19 Identifies Patients with Low or High Risk for Side Effects in …

W Steimer, K Zopf, S von Amelunxen, H Pfeiffer… - Clinical …, 2005 - academic.oup.com
Background: Amitriptyline has been replaced in many countries by alternative and more
expensive drugs based on claims of improved tolerability and toxicity and despite slightly …

Helminths and malignancy

BJ Vennervald, K Polman - Parasite Immunology, 2009 - Wiley Online Library
It has been estimated that chronic infections with viruses, bacteria and parasites contribute
to 17· 8% of the global burden of cancer, although only a relatively small proportion of the …

[PDF][PDF] Aetiology of cancer in Asia

S Park, J Bae, BH Nam, KY Yoo - Asian Pac J Cancer Prev, 2008 - academia.edu
Cancer has become the leading cause of death in many Asian countries. There is an
increasing trend in breast, prostate and colon cancers, which are considered as typical of …