Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease

EL Konrath, CS Passos, LC Klein-Júnior… - Journal of Pharmacy …, 2013 - academic.oup.com
Objectives The inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown
of acetylcholine, is currently the main pharmacological strategy available for Alzheimer's …

Bisbenzylisoquinoline alkaloids

C Weber, T Opatz - The Alkaloids: Chemistry and Biology, 2019 - Elsevier
The present review covers the literature on bisbenzylisoquinoline alkaloids from 1999
through early 2018. About 500 natural products belong to this large alkaloid class, of which …

[HTML][HTML] The promising role of natural products in Alzheimer's disease

MM da Rosa, LC de Amorim, JV de Oliveira Alves… - Brain Disorders, 2022 - Elsevier
Experimental studies support the discussion of the use of bioactive products of natural
products as novel antioxidants sources of neuroprotection against neurodegeneration …

Natural products as sources of new lead compounds for the treatment of Alzheimer's disease

L Huang, T Su, X Li - Current topics in medicinal chemistry, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is the most prevalent form of dementia and affects approximately
24 million people worldwide. One possible approach for the treatment of this disease is the …

Protective effects of Liensinine, Isoliensinine, and Neferine on PC12 cells injured by amyloid‐β

XL Meng, SY Liu, JS Xue, JM Gou… - Journal of Food …, 2022 - Wiley Online Library
Excessive accumulation of amyloid‐β (Aβ) is the leading cause of Alzheimer's disease (AD).
Liensinine, Isoliensinine, and Neferine are main alkaloids in lotus seed embryos. In this …

Antiproliferative Dimeric Aporphinoid Alkaloids from the Roots of Thalictrum cultratum

DH Li, JY Li, CM Xue, T Han, CM Sai… - Journal of natural …, 2017 - ACS Publications
Inspired by the intriguing structures and bioactivities of dimeric alkaloids, 11 new
thalifaberine-type aporphine-benzylisoquinoline alkaloids, thalicultratines A–K, a …

Leishmanicidal and cytotoxic activity from plants used in Tacana traditional medicine (Bolivia)

D Arévalo-Lopéz, N Nina, JC Ticona, I Limachi… - Journal of …, 2018 - Elsevier
Abstract Etnopharmacological relevance Thirty-eight Tacana medicinal plant species used
to treat skin problems, including leishmania ulcers, skin infections, inflammation and wound …

Biomolecular Evaluation of Lavandula stoechas L. for Nootropic Activity

A Mushtaq, R Anwar, UF Gohar, M Ahmad, RA Marc… - Plants, 2021 - mdpi.com
Lavandula Stoechas L. is widely known for its pharmacological properties. This study was
performed to identify its biomolecules, which are responsible for enhancement of memory. L …

Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin‐Induced Cardiotoxicity in Rats

OE Olorundare, AA Adeneye, AO Akinsola… - Journal of …, 2020 - Wiley Online Library
Doxorubicin is widely applied in hematological and solid tumor treatment but limited by its off‐
target cardiotoxicity. Thus, cardioprotective potential and mechanism (s) of CVE in DOX …

Acetylcholinesterase inhibitory activities and bioguided fractionation of the Ocotea percoriacea extracts: HPLC-DAD-MS/MS characterization and molecular modeling …

DSA Cassiano, IMA Reis, I de Oliveira Estrela… - … Biology and Chemistry, 2019 - Elsevier
In vitro acetylcholinesterase activities of the hexane, dichloromethane, ethyl acetate, n-
butanol and aqueous extracts of leaves of Ocotea percoriacea Kosterm.(Lauraceae) were …