Microtubules as a potential platform for energy transfer in biological systems: a target for implementing individualized, dynamic variability patterns to improve organ …
Y Ilan - Molecular and Cellular Biochemistry, 2023 - Springer
Variability characterizes the complexity of biological systems and is essential for their
function. Microtubules (MTs) play a role in structural integrity, cell motility, material transport …
function. Microtubules (MTs) play a role in structural integrity, cell motility, material transport …
Mechanics of microtubules
Microtubules are rigid cytoskeletal filaments, and their mechanics affect cell morphology and
cellular processes. For instance, microtubules for the support structures for extended …
cellular processes. For instance, microtubules for the support structures for extended …
Tubulin acetylation protects long-lived microtubules against mechanical ageing
Long-lived microtubules endow the eukaryotic cell with long-range transport abilities. While
long-lived microtubules are acetylated on Lys40 of α-tubulin (αK40), acetylation takes place …
long-lived microtubules are acetylated on Lys40 of α-tubulin (αK40), acetylation takes place …
Thermal fluctuations of grafted microtubules provide evidence of a length-dependent persistence length
Microtubules are hollow cylindrical structures that constitute one of the three major classes
of cytoskeletal filaments. On the mesoscopic length scale of a cell, their material properties …
of cytoskeletal filaments. On the mesoscopic length scale of a cell, their material properties …
[HTML][HTML] Cell line-directed breast cancer research based on glucose metabolism status
Metabolic reprogramming is a potential hallmark of tumor cells to support continuous
proliferation. Metabolic heterogeneity in breast cancer patients has been highlighted as the …
proliferation. Metabolic heterogeneity in breast cancer patients has been highlighted as the …
Microtubule architecture: inspiration for novel carbon nanotube-based biomimetic materials
F Pampaloni, EL Florin - Trends in biotechnology, 2008 - cell.com
Microtubules are self-assembling biological nanotubes that are essential for cell motility, cell
division and intracellular trafficking. Microtubules have outstanding mechanical properties …
division and intracellular trafficking. Microtubules have outstanding mechanical properties …
Taxol allosterically alters the dynamics of the tubulin dimer and increases the flexibility of microtubules
A Mitra, D Sept - Biophysical journal, 2008 - cell.com
Taxol is a commonly used antitumor agent that hyperstabilizes microtubules and prevents
cell division. The interaction of Taxol with tubulin and the microtubule has been studied …
cell division. The interaction of Taxol with tubulin and the microtubule has been studied …
High-frequency electric field and radiation characteristics of cellular microtubule network
Microtubules are important structures in the cytoskeleton, which organizes the cell. Since
microtubules are electrically polar, certain microtubule normal vibration modes efficiently …
microtubules are electrically polar, certain microtubule normal vibration modes efficiently …
[HTML][HTML] Cardioprotective effect of royal jelly on paclitaxel-induced cardio-toxicity in rats
H Malekinejad, S Ahsan… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Objective (s): Paclitaxel is a potent chemotherapy agent with severe side effects, including
allergic reactions, cardiovascular problems, complete hair loss, joint and muscle pain, which …
allergic reactions, cardiovascular problems, complete hair loss, joint and muscle pain, which …
Microtubule elasticity: connecting all-atom simulations with continuum mechanics
D Sept, FC MacKintosh - Physical review letters, 2010 - APS
The mechanical properties of microtubules have been extensively studied using a wide
range of biophysical techniques, seeking to understand the mechanics of these cylindrical …
range of biophysical techniques, seeking to understand the mechanics of these cylindrical …