There has been considerable advancement over the last few years in the treatment of
osteoarthritis, common chronic disease and a major cause of disability in older adults. In this …

Joint distraction, the prolonged mechanical separation of the bones at a joint, has emerged
as a joint-preserving treatment for end-stage osteoarthritis, with the gradually growing …

The aim of this study was to evaluate the benefit provided by intraosseous infiltration
combined with intra-articular injection of platelet-rich plasma to treat mild and moderate …

Background In recent years, platelet-rich plasma (PRP) injections for osteoarthritis (OA)
have been widely promoted in clinical practice, but their effectiveness is controversial …

Platelet concentrates (PCs), mostly represented by platelet-rich plasma (PRP) and platelet-
rich fibrin (PRF) are autologous biological blood-derived products that may combine …

Purpose To investigate the available literature on the use of bone marrow aspirate
concentrate (BMAC) and summarize the current evidence supporting its potential for the …

Background The use of biologic therapies for the management of knee osteoarthritis has
increased, despite insufficient evidence of efficacy. Our aim was to complete a systematic …

Knee pain is second only to the back as the most commonly reported area of pain in the
human body. With an overall prevalence of 46.2%, its impact on disability, lost productivity …

Purpose Subchondral bone is becoming a treatment target for knee OA patients, with
promising early findings on the use of bone marrow aspirate concentrate (BMAC). The aim …

Aging and age-related changes impact the quality of life (QOL) in elderly with a decline in
movement, cognitive abilities and increased vulnerability towards age-related diseases …