Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Colorectal cancer (CRC) being one of the most common malignancies, has a significant
death rate, especially when detected at an advanced stage. In most cases, the fundamental …

Molecular signaling pathways play a significant role in the regulation of biological
mechanisms, and their abnormal expression can provide the conditions for cancer …

Colorectal cancer (CRC) is one of the most common digestive diseases worldwide. It has
steadily ascended to the top three cancers in terms of incidence and mortality. The primary …

The progress of genetic engineering in the 1970s brought about a paradigm shift in genome
editing technology. The clustered regularly interspaced short palindromic repeats/CRISPR …

MicroRNAs (miRNAs) are non‑coding RNAs (ncRNAs) that can post‑transcriptionally
suppress targeted genes. Dysregulated miRNAs are associated with a variety of diseases …

Colorectal cancer (CRC) is ranked as the third most common cancer and second deadliest
cancer in both men and women in the world. Currently, the cure rate and 5-year survival rate …

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection and is characterized by a hyperinflammatory state accompanied by …

Background The development of drug resistance and high mortality rates are the major
problems observed in non-small cell lung cancer (NSCLC). Biomarkers indicating and …

Despite the dramatic advances in our understanding of the etiology of colorectal cancer
(CRC) in recent decades, effective therapeutic strategies are still urgently needed …