Neutrophil gelatinase-associated lipocalin (NGAL) is a 25-kDa protein that is secreted
mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production …

Neutrophil gelatinase-associated lipocalin (NGAL) is a small circulating protein that is highly
modulated in a wide variety of pathological situations, making it a useful biomarker of …

Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

Cell senescence is a fundamental mechanism of aging and appears to play vital roles in the
onset and prognosis of cardiovascular disease, fibrotic pulmonary disease, liver disease …

Atherosclerosis and its clinical manifestations, coronary and cerebral artery diseases, are
the most common cause of death worldwide. The main pathophysiological mechanism for …

Carotid artery stenosis (CAS), an atherosclerotic disease of the carotid artery, is one of the
leading causes of transient ischemic attacks (TIA) and cerebrovascular attacks (CVA). The …

Extracellular matrix (ECM) remodeling is required for many physiological and pathological
processes. Metalloproteinases (MMPs) are endopeptidases which are able to degrade …

Carotid stenosis is characterized by the progressive narrowing of the carotid arteries due to
the formation of atherosclerotic plaque, which can lead to stroke and death as major …

Objective Peripheral arterial disease (PAD) is the most prevalent cardiovascular (CV)
condition globally. Despite the high CV risk of PAD patients, no reliable predictors of …

Background Neutrophil gelatinase-associated lipocalin (NGAL), an acute phase protein
released by neutrophils, has been described as biomarker of inflammatory states. Type 2 …