Invasive candidiasis in critical care: challenges and future directions

C Logan, I Martin-Loeches, T Bicanic - Intensive care medicine, 2020 - Springer
Invasive candidiasis is the most common critical care-associated fungal infection with a
crude mortality of~ 40–55%. Important factors contributing to risk of invasive candidiasis in …

The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

[HTML][HTML] European candidaemia is characterised by notable differential epidemiology and susceptibility pattern: Results from the ECMM Candida III study

MC Arendrup, S Arikan-Akdagli, KM Jørgensen… - Journal of Infection, 2023 - Elsevier
The objectives of this study were to assess Candida spp. distribution and antifungal
resistance of candidaemia across Europe. Isolates were collected as part of the third ECMM …

Emergence of resistant Candida glabrata in Germany

AM Aldejohann, M Herz, R Martin… - JAC-antimicrobial …, 2021 - academic.oup.com
Background Candida glabrata is the second leading fungal pathogen causing candidaemia
and invasive candidiasis in Europe. This yeast is recognized for its rapid ability to acquire …

Antifungal Resistance in Clinical Isolates of Candida glabrata in Ibero-America

E Martinez-Herrera, MG Frias-De-Leon… - Journal of Fungi, 2021 - mdpi.com
In different regions worldwide, there exists an intra-and inter-regional variability in the rates
of resistance to antifungal agents in Candida glabrata, highlighting the importance of …

[HTML][HTML] Azole resistance in Candida glabrata clinical isolates from global surveillance is associated with efflux overexpression

M Castanheira, LM Deshpande, AP Davis… - Journal of Global …, 2022 - Elsevier
Objectives We evaluated the azole resistance mechanisms and epidemiology of fluconazole-
resistant Candida glabrata from a global survey. Methods A total of 2992 Candida spp …

Low level of antifungal resistance of Candida glabrata blood isolates in Turkey: Fluconazole minimum inhibitory concentration and FKS mutations can predict …

A Arastehfar, F Daneshnia, M Salehi, M Yaşar… - Mycoses, 2020 - Wiley Online Library
Background Candida glabrata is the third leading cause of candidaemia in Turkey; however,
the data regarding antifungal resistance mechanisms and genotypic diversity in association …

Candida glabrata (Nakaseomyces glabrata): A systematic review of clinical and microbiological data from 2011 to 2021 to inform the World Health Organization …

J Beardsley, HY Kim, A Dao, S Kidd… - Medical …, 2024 - academic.oup.com
Recognising the growing global burden of fungal infections, the World Health Organization
(WHO) established an advisory group consisting of experts in fungal diseases to develop a …

Antifungal susceptibility trend and analysis of resistance mechanism for Candida species isolated from bloodstream at a Japanese university hospital

T Sakagami, T Kawano, K Yamashita, E Yamada… - Journal of Infection and …, 2019 - Elsevier
We compared the susceptibility of six commercially available antifungal agents (fluconazole,
itraconazole, voriconazole, caspofungin, micafungin, and amphotericin B) against 133 …

First multicentre report of in vitro resistance rates in candidaemia isolates in Turkey

S Arikan-Akdagli, D Gülmez, Ö Doğan… - Journal of global …, 2019 - Elsevier
Objectives This study investigated the antifungal resistance rates of isolates from
candidaemia patients in 12 tertiary-care centres in Turkey. Methods A total of 1991 Candida …