Integrating bulk and single cell RNA-seq refines transcriptomic profiles of specific C. elegans neurons
Neuron-specific morphology and function are fundamentally tied to differences in gene
expression across the nervous system. We previously generated a single cell RNA-seq …
expression across the nervous system. We previously generated a single cell RNA-seq …
Estimating cell-type-specific gene co-expression networks from bulk gene expression data with an application to Alzheimer's disease
Inferring and characterizing gene co-expression networks has led to important insights on
the molecular mechanisms of complex diseases. Most co-expression analyses to date have …
the molecular mechanisms of complex diseases. Most co-expression analyses to date have …