Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a …
Background: The FIDELIO-DKD trial (Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease) evaluated the effect of the nonsteroidal, selective …
PK Whelton, RM Carey, WS Aronow, DE Casey… - Journal of the American …, 2018 - jacc.org
As early as the 1920s, and subsequently in the 1959 Build and Blood Pressure Study (S1. 5- 1) of almost 5 million adults insured between 1934 and 1954, a strong direct relationship …
Background There is conflicting evidence, relying on heterogeneous studies, as to whether aldosterone excess is responsible for an increased risk of cardiovascular and …
JW Funder, RM Carey, F Mantero… - The Journal of …, 2016 - academic.oup.com
Objective: To develop clinical practice guidelines for the management of patients with primary aldosteronism. Participants: The Task Force included a chair, selected by the …
GL Hundemer, GC Curhan, N Yozamp… - The lancet Diabetes & …, 2018 - thelancet.com
Background Mineralocorticoid receptor (MR) antagonists are the recommended medical therapy for primary aldosteronism. Whether this recommendation effectively reduces …
TA Williams, JWM Lenders, P Mulatero… - The lancet Diabetes & …, 2017 - thelancet.com
Background Although unilateral primary aldosteronism is the most common surgically correctable cause of hypertension, no standard criteria exist to classify surgical outcomes …
S Monticone, J Burrello, D Tizzani, C Bertello… - Journal of the American …, 2017 - jacc.org
Background: Despite being widely recognized as the most common form of secondary hypertension, among the general hypertensive population the true prevalence of primary …
Primary aldosteronism is a common cause of hypertension and is a risk factor for cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …