[PDF][PDF] Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the …

J Boren, MJ Chapman, RM Krauss… - European heart …, 2020 - academic.oup.com
OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

TREM2 in the pathogenesis of AD: a lipid metabolism regulator and potential metabolic therapeutic target

RY Li, Q Qin, HC Yang, YY Wang, YX Mi, YS Yin… - Molecular …, 2022 - Springer
Triggering receptor expressed on myeloid cells 2 (TREM2) is a single-pass transmembrane
immune receptor that is mainly expressed on microglia in the brain and macrophages in the …

Coronary atherosclerotic plaque activity and future coronary events

A Moss, M Daghem, E Tzolos, MN Meah… - JAMA …, 2023 - jamanetwork.com
Importance Recurrent coronary events in patients with recent myocardial infarction remain a
major clinical problem. Noninvasive measures of coronary atherosclerotic disease activity …

Pathophysiology of aortic stenosis and future perspectives for medical therapy

KH Zheng, E Tzolos, MR Dweck - Cardiology clinics, 2020 - cardiology.theclinics.com
Calcific aortic stenosis (AS) is the most common valve disease in the high-income countries
and is set to become a major health care burden with an aging population. 1 It is …

Coronary 18F-Fluoride Uptake and Progression of Coronary Artery Calcification

MK Doris, MN Meah, AJ Moss… - Circulation …, 2020 - Am Heart Assoc
Background Positron emission tomography (PET) using 18F-sodium fluoride (18F-fluoride)
to detect microcalcification may provide insight into disease activity in coronary …

Bypass grafting and native coronary artery disease activity

J Kwiecinski, E Tzolos, AJ Fletcher, J Nash… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to describe the potential of 18F-sodium fluoride (18F-
NaF) positron emission tomography (PET) to identify graft vasculopathy and to investigate …

Atherosclerosis imaging with 18F-sodium fluoride PET: state-of-the-art review

PF Høilund-Carlsen, M Sturek, A Alavi… - European Journal of …, 2020 - Springer
Purpose We examined the literature to elucidate the role of 18F-sodium fluoride (NaF)-PET
in atherosclerosis. Methods Following a systematic search of PubMed/MEDLINE, Embase …

Two-faced Janus: the dual role of macrophages in atherosclerotic calcification

OJ Waring, NT Skenteris, EAL Biessen… - Cardiovascular …, 2022 - academic.oup.com
Calcification is an independent predictor of atherosclerosis-related cardiovascular events.
Microcalcification is linked to inflamed, unstable lesions, in comparison to the fibrotic stable …

18F-Sodium Fluoride (18F-NaF) for Imaging Microcalcification Activity in the Cardiovascular System

E Tzolos, MR Dweck - Arteriosclerosis, Thrombosis, and Vascular …, 2020 - Am Heart Assoc
Accumulating preclinical and clinical evidence suggests that calcification is one of the body's
primary responses to injury and a key pathological feature of cardiovascular disease …

Temporal changes in coronary 18F-fluoride plaque uptake in patients with coronary atherosclerosis

M Daghem, PD Adamson, KL Wang… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Coronary 18F-sodium fluoride (18F-fluoride) uptake is a marker of both atherosclerotic
disease activity and disease progression. It is currently unknown whether there are rapid …