NF-κB Pathway and Its Inhibitors: A Promising Frontier in the Management of Alzheimer's Disease
The nuclear factor kappa B (NF-κB) pathway has emerged as a pivotal player in the
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …
Clinical, Immunological, and Genetic Features in Patients with NFKB1 and NFKB2 Mutations: a Systematic Review
Background Inborn errors of immunity (IEIs) encompass various diseases with diverse
clinical and immunological symptoms. Determining the genotype–phenotype of different …
clinical and immunological symptoms. Determining the genotype–phenotype of different …
Regulation of the microglial polarization for alleviating neuroinflammation in the pathogenesis and therapeutics of major depressive disorder
YF Wang, CY Chen, L Lei, Y Zhang - Life Sciences, 2025 - Elsevier
Major depressive disorder (MDD), as a multimodal neuropsychiatric and neurodegenerative
illness with high prevalence and disability rates, has become a burden to world health and …
illness with high prevalence and disability rates, has become a burden to world health and …
Interleukin-1 increases SERPINE1 expression in human granulosa-lutein cell via P50/P52 signaling pathways
Y Xiang, S Liu, S Wan, Q Chen, Y Song, G Feng… - Molecular and Cellular …, 2024 - Elsevier
It has been reported that immune factors are associated with the occurrence of polycystic
ovary syndrome (PCOS). Interleukin-1 (IL-1) is a member of the interleukin family that widely …
ovary syndrome (PCOS). Interleukin-1 (IL-1) is a member of the interleukin family that widely …
[PDF][PDF] Bioinformatics screening of gene expression profile and diagnostic application of meningeal carcinoma.
J Li, Y Zhang, KX Bai, XJ Qi, Y Zhao… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: The aim of this study was to research gene expression profiles and diagnostic
applications of meningeal carcinoma based on bioinformatics. MATERIALS AND …
applications of meningeal carcinoma based on bioinformatics. MATERIALS AND …
[HTML][HTML] Enhancing cancer immunotherapy: Nanotechnology-mediated immunotherapy overcoming immunosuppression
Y Chen, Q Zhou, Z Jia, N Cheng, S Zhang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Immunotherapy is an important cancer treatment method that offers hope for curing cancer
patients. While immunotherapy has achieved initial success, a major obstacle to its …
patients. While immunotherapy has achieved initial success, a major obstacle to its …
Machine Learning and Bioinformatics Approaches to Identify the Candidate Biomarkers in Severe Asthma.
F Zhang, X Weng, J Zhu, Q Tang, M Lei… - The Journal of Asthma …, 2024 - europepmc.org
Severe asthma is characterized by a poor level of control that severely affects the patient's
life and prognosis. However, the underlying pathogenic mechanisms remain unknown …
life and prognosis. However, the underlying pathogenic mechanisms remain unknown …
NFKB pathway mutations in the Iranian cohort
Background: Investigating and documenting novel mutations within inborn errors of
immunity (IEIs) has demonstrably enriched our comprehension of disease causation. This …
immunity (IEIs) has demonstrably enriched our comprehension of disease causation. This …