Breast cancer is one of the most common malignancies among women throughout the world
and is the major cause of most cancer-related deaths. Several explanations account for the …

The network approach is quickly becoming a fundamental building block of computational
methods aiming at elucidating the mechanism of action (MoA) and therapeutic effect of …

Background Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic
malignancy. Due to its wide heterogeneity, PDAC acts aggressively and responds poorly to …

This paper presents a novel approach to data clustering by introducing the Chaotic Quasi-
Opposition-Based Learning Marine Predators Algorithm (CQOBLMPA). The primary …

Next-generation sequencing approaches and genome-wide studies have become essential
for characterizing the mechanisms of human diseases. Consequently, many researchers …

Background: Large-scale screening of drug sensitivity on cancer cell models can mimic in
vivo cellular behavior providing wider scope for biological research on cancer. Since the …

Cervical lymph node metastasis is the leading cause of poor prognosis in oral tongue
squamous cell carcinoma and also occurs in the early stages. The current clinical diagnosis …

Various feature selection algorithms have been proposed to identify cancer prognostic
biomarkers. In recent years, however, their reproducibility is criticized. The performance of …

Network biology has become a key tool in unravelling the mechanisms of complex diseases.
Detecting dys-regulated subnetworks from molecular networks is a task that needs efficient …

Predictive genomic biomarkers, often genomic aberrations such as mutations or
copynumber alterations with an associated targeted therapy (ie, actionable genomic …