Mitochondria are dynamic organelles that have essential metabolic and regulatory functions.
Earlier studies using electron microscopy (EM) revealed an immense diversity in the …

Mitochondria are complex organelles with two membranes. Their architecture is determined
by characteristic folds of the inner membrane, termed cristae. Recent studies in yeast and …

Mitochondrial function is critically dependent on the folding of the mitochondrial inner
membrane into cristae; indeed, numerous human diseases are associated with aberrant …

Cristae are high‐curvature structures in the inner mitochondrial membrane (IMM) that are
crucial for ATP production. While cristae‐shaping proteins have been defined, analogous …

Mitochondria are highly dynamic organelles that exhibit a complex inner architecture. They
exhibit a smooth outer membrane and a highly convoluted inner membrane that forms …

Mitochondrial cristae are the main site for oxidative phosphorylation, which is critical for
cellular energy production. Upon different physiological or pathological stresses …

Significance: Our current knowledge of the pathophysiology and molecular mechanisms
causing psychiatric disorders is modest, but genetic susceptibility and environmental factors …

Mitochondria play central roles in cellular energetics, metabolism and signalling. Efficient
respiration, mitochondrial quality control, apoptosis and inheritance of mitochondrial DNA …

Within cellular structures, compartmentalization is the concept of spatial segregation of
macromolecules, metabolites, and biochemical pathways. Therefore, this concept bridges …

Mitochondria are centers of energy metabolism. The mitochondrial network is shaped by
mitochondrial dynamics, including the processes of mitochondrial fission and fusion and …