Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

MJ Rohovie, M Nagasawa… - … & translational medicine, 2017 - Wiley Online Library
Most drug therapies distribute the agents throughout the entire body, even though the drugs
are typically only needed at specific tissues. This often limits dosage and causes discomfort …

Mechanisms of virus assembly

JD Perlmutter, MF Hagan - Annual review of physical chemistry, 2015 - annualreviews.org
Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

On virus growth and form

R Zandi, B Dragnea, A Travesset, R Podgornik - Physics Reports, 2020 - Elsevier
We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Protein cage assembly across multiple length scales

WM Aumiller, M Uchida, T Douglas - Chemical Society Reviews, 2018 - pubs.rsc.org
Within the materials science community, proteins with cage-like architectures are being
developed as versatile nanoscale platforms for use in protein nanotechnology. Much effort …

Physics of viral dynamics

RF Bruinsma, GJL Wuite, WH Roos - Nature Reviews Physics, 2021 - nature.com
Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Elastic instability of a crystal growing on a curved surface

G Meng, J Paulose, DR Nelson, VN Manoharan - Science, 2014 - science.org
Although the effects of kinetics on crystal growth are well understood, the role of substrate
curvature is not yet established. We studied rigid, two-dimensional colloidal crystals growing …

Controlling the self-assembly of biomolecules into functional nanomaterials through internal interactions and external stimulations: A review

L Wang, C Gong, X Yuan, G Wei - Nanomaterials, 2019 - mdpi.com
Biomolecular self-assembly provides a facile way to synthesize functional nanomaterials.
Due to the unique structure and functions of biomolecules, the created biological …

Equilibrium mechanisms of self-limiting assembly

MF Hagan, GM Grason - Reviews of modern physics, 2021 - APS
Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …

In vitro assembly of virus-like particles and their applications

DT Le, KM Müller - Life, 2021 - mdpi.com
Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery.
Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous …