Regulatory T Cells in Mycobacterium tuberculosis Infection

P Cardona, PJ Cardona - Frontiers in immunology, 2019 - frontiersin.org
Anti-inflammatory regulatory T cells have lately attracted attention as part of the immune
response to Mycobacterium tuberculosis infection, where they counterbalance the protective …

Mycobacterium tuberculosis infection and vaccine development

J Tang, WC Yam, Z Chen - Tuberculosis, 2016 - Elsevier
Summary Following HIV/AIDS, tuberculosis (TB) continues to be the second most deadly
infectious disease in humans. The global TB prevalence has become worse in recent years …

Erythropoietin and bacillus calmette–guérin vaccination mitigate 3-nitropropionic acid-induced Huntington-like disease in rats by modulating the PI3K/Akt/mTOR …

MA Senousy, ME Hanafy, N Shehata… - ACS chemical …, 2022 - ACS Publications
Oxidative stress and mitochondrial dysfunction are among the mechanisms expected to
explain the pathogenesis of Huntington's disease. Erythropoietin (EPO) and the Bacillus …

Bacillus Calmette‐Guerin vaccine‐mediated neuroprotection is associated with regulatory T‐cell induction in the 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine …

G Laćan, H Dang, B Middleton… - Journal of …, 2013 - Wiley Online Library
We previously showed that, in the 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP)
mouse model of Parkinson's disease (PD), vaccination with bacillus Calmette‐Guerin (BCG) …

Immunotherapeutic Effects of Different Doses of Mycobacterium tuberculosis ag85a/b DNA Vaccine Delivered by Electroporation

Y Liang, L Cui, L Xiao, X Liu, Y Yang, Y Ling… - Frontiers in …, 2022 - frontiersin.org
Background Tuberculosis (TB) is a major global public health problem. New treatment
methods on TB are urgently demanded. Methods Ninety-six female BALB/c mice were …

DNA vaccines against tuberculosis

N Bruffaerts, K Huygen, M Romano - Expert opinion on biological …, 2014 - Taylor & Francis
Introduction: Tuberculosis (TB) remains a major health problem and novel vaccination
regimens are urgently needed. Areas covered: DNA vaccines against TB have been tested …

Integrating knowledge of Mycobacterium tuberculosis pathogenesis for the design of better vaccines

F Mascart, C Locht - Expert review of vaccines, 2015 - Taylor & Francis
Today, tuberculosis (TB) still remains one of the main global causes of mortality and
morbidity, and an effective vaccine against both TB disease and Mycobacterium tuberculosis …

Vaccines and the regulatory arm of the immune system. An overview from the Trypanosoma cruzi infection model

G Cabrera, I Marcipar - Vaccine, 2019 - Elsevier
The knowledge that the immune system is composed of a regulatory/suppressor arm added
a new point of view to better understand the nature of several pathologies including cancer …

Adjunct strategies for tuberculosis vaccines: modulating key immune cell regulatory mechanisms to potentiate vaccination

L Jayashankar, R Hafner - Frontiers in immunology, 2016 - frontiersin.org
Tuberculosis (TB) remains a global health threat of alarming proportions, resulting in 1.5
million deaths worldwide. The only available licensed vaccine, Bacillus Calmette–Guérin …

Attenuation of experimental asthma by mycobacterial protein combined with CpG requires a TLR 9‐dependent IFN‐γ‐CCR 2 signalling circuit

RQ Prado, TB Bertolini, AR Piñeros… - Clinical & …, 2015 - Wiley Online Library
Background Allergic asthma is a chronic pulmonary disease characterized by a Th2
inflammatory response. The modulation of a Th2 immune response based on immune …