Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Enantioselective synthesis with small-molecule chiral hydrogen-bond donors has emerged
as a frontier of research in the field of asymmetric catalysis. Organic chemists have …

The fundamental role of the Lewis-acid catalyst lies in the activation of the CdX bond (X) O,
NR, CR2), thereby decreasing the LUMO energy and promoting nucleophilic addition to the …

Organic synthesis is one of the most successful and useful disciplines of science and mainly
involves the construction of carbon-carbon bond (s) and carbon-heteroatom bond (s) and …

Abstract The legacy of Gilbert Newton Lewis (1875–1946) pervades the lexicon of chemical
bonding and reactivity. The power of his concept of donor–acceptor bonding is evident in the …

After an initial period of validating asymmetric organocatalysis by using a wide range of
important model reactions that constitute the essential tools of organic synthesis, the time …

Asymmetric organocatalysis is becoming one of the main tools for the synthesis of chiral
compounds that are needed as medicines, crop protection agents, and other bioactive …

Catalytic asymmetric synthesis has received considerable attention over the past few
decades, becoming a highly dynamic area of chemical research with significant …

The enantioselective production of compounds is a central theme in current research. The
broad utility of synthetic chiral molecules as single-enantiomer pharmaceuticals, in …

The creation of carbon-carbon bonds remains an important challenge in organic synthesis.
Numerous reactions for the formation of carbon-carbon bonds have been discovered and …