Knowledge gaps that hamper prevention and control of Mycobacterium avium subspecies paratuberculosis infection

HW Barkema, K Orsel, SS Nielsen… - Transboundary and …, 2018 - Wiley Online Library
In the last decades, many regional and country‐wide control programmes for Johne's
disease (JD) were developed due to associated economic losses, or because of a possible …

Pathogenesis, Molecular Genetics, and Genomics of Mycobacterium avium subsp. paratuberculosis, the Etiologic Agent of Johne's Disease

G Rathnaiah, DK Zinniel, JP Bannantine… - Frontiers in veterinary …, 2017 - frontiersin.org
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of Johne's
disease in ruminants causing chronic diarrhea, malnutrition, and muscular wasting …

Mechanisms of antimicrobial action of cinnamon and oregano oils, cinnamaldehyde, carvacrol, 2, 5-dihydroxybenzaldehyde, and 2-hydroxy-5-methoxybenzaldehyde …

SW Nowotarska, K Nowotarski, IR Grant, CT Elliott… - Foods, 2017 - mdpi.com
The antimicrobial modes of action of six naturally occurring compounds, cinnamon oil,
cinnamaldehyde, oregano oil, carvacrol, 2, 5-dihydroxybenzaldehyde, and 2-hydroxy-5 …

A single dose polyanhydride-based nanovaccine against paratuberculosis infection

A Thukral, K Ross, C Hansen, Y Phanse… - npj Vaccines, 2020 - nature.com
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) causes Johne's
disease in ruminants and is characterized by chronic gastroenteritis leading to heavy …

Immuno-reactivity evaluation of Mce-truncated subunit candidate vaccine against Mycobacterium avium subspecies paratuberculosis challenge in the goat models

M Haghkhah, Z Hemati, A Derakhshandeh… - BMC Veterinary …, 2023 - Springer
Background Detection of an appropriate antigen with high immunogenicity can be a big step
in the production of an effective vaccine for control of Johne's disease (JD). The aim of this …

A protective vaccine against Johne's disease in cattle

Y Phanse, CW Wu, AJ Venturino, C Hansen, K Nelson… - Microorganisms, 2020 - mdpi.com
Johne's disease (JD) caused by Mycobacterium avium subsp. paratuberculosis (M.
paratuberculosis) is a chronic infection characterized by the development of granulomatous …

Evaluation of Mycobacterium avium subsp. paratuberculosis isocitrate lyase (IcL) and ABC transporter (BacA) knockout mutants as vaccine candidates

R Eshraghisamani, R Arrazuria, L Luo… - Frontiers in Cellular and …, 2023 - frontiersin.org
There has been little success in controlling Johne's disease, caused by Mycobacterium
avium subsp. paratuberculosis, due to suboptimal diagnostics and the ineffectiveness of …

Immunological evaluation of goats immunized with a commercial vaccine against Johne's disease

JP Bannantine, JR Stabel, V Kapur - Vaccines, 2022 - mdpi.com
Johne's disease affects ruminants causing an economic burden to dairy, meat and wool
industries. Vaccination against Mycobacterium avium subspecies paratuberculosis (Map) …

Immunogenicity and efficacy of an oral live-attenuated vaccine for bovine Johne's disease

R Eshraghisamani, A Facciuolo… - Frontiers in …, 2024 - frontiersin.org
Mycobacterium avium subsp. paratuberculosis (MAP), the etiological agent of Johne's
disease (JD) in ruminants, establishes a prolonged and often lifelong enteric infection. The …

Biomarkers for early stages of Johne's Disease infection and immunization in goats

A Berry, C Wu, AJ Venturino, AM Talaat - Frontiers in Microbiology, 2018 - frontiersin.org
Background: Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) is the
causative agent of Johne's disease, a chronic enteric infection of ruminants. Infection occurs …