Over the last few decades, chitosan has become a good candidate for tissue engineering
applications. Derived from chitin, chitosan is a unique natural polysaccharide with …

From 20th century, chitosan, a natural polysaccharide, has received much attention for use
in biomedical applications thanks to its remarkable properties, such as biodegradability …

With increased diabetes incidence, diabetic wound healing is one of the most common
diabetes complications and is characterized by easy infection, chronic inflammation, and …

Notwithstanding the remarkable progress in the clinical treatment of ischemic disease,
proangiogenic drugs mostly suffer from their abnormal angiogenesis and potential cancer …

Emerging evidence suggests that dysfunctional macrophages can cause chronic
inflammation and impair tissue regeneration in diabetic wounds. Therefore, improving …

Naturally-derived biomaterials have been used for decades in multiple regenerative
medicine applications. From the simplest cell microcarriers made of collagen or alginate, to …

Ischemic diseases lead to considerable morbidity and mortality, yet conventional clinical
treatment strategies for therapeutic angiogenesis fall short of being impactful. Despite the …

Chitosan is a unique natural resourced polysaccharide derived from chitin with special
biocompatibility, biodegradability, and antimicrobial activity. During the past three decades …

Preserving the bioactivity of growth factors (GFs) and mimicking their in vivo supply patterns
are challenging in the development of GFs-based bone grafts. In this study, we develop a 2 …

Severe wounds result in large lesions and/or loss of function of the affected areas. The
treatment of wounds has challenged health professionals due to its complexity, especially in …